Results 61 to 70 of about 3,514 (186)

Integrated green extraction of phenolic compounds and fermentable sugars from grapefruit peel using ultrasound and enzymatic hydrolysis

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1839-1851, February 2026.
Abstract BACKGROUND Valorizing sugar‐rich food waste in biorefineries offers a sustainable route to bio‐based products. Grapefruit peel (GP), representing about 50% of the fruit's weight, is rich in sugars (soluble and insoluble) and polyphenols such as flavonoids.
María del Prado García‐Aparicio, María Castro‐Puyana, María Luisa Marina   +2 more
wiley   +1 more source

Convergent evolution of the UbiA prenyltransferase family underlies the independent acquisition of furanocoumarins in plants

New Phytologist, 2019
Summary Furanocoumarins (FCs) are plant‐specialized metabolites with potent allelochemical properties. The distribution of FCs is scattered with a chemotaxonomical tendency towards four distant families with highly similar FC pathways.
R. Munakata, S. Kitajima, A. Nuttens, Kanade Tatsumi, Tomoya Takemura, Takuji Ichino, Gianni Galati, S. Vautrin, H. Bergès, Jérémy Grosjean, F. Bourgaud, A. Sugiyama, A. Hehn, K. Yazaki   +13 more
semanticscholar   +1 more source

A Coumarin Compound Derived From Zanthoxylum avicennae Reduces the Pathogenicity of Fusarium verticillioides by Directly Binding to and Inhibiting Glycoside Hydrolase 3 Activity

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
Luvangetin, a coumarin compound from Zanthoxylum avicennae roots, affects the cell wall degradation capacity and pathogenicity of Fusarium verticillioides on maize. Integrated transcriptomic, proteomic and in vitro activity analyses revealed that it binds to three critical sites of the Fusarium glycoside hydrolase 3 family (GH3) β‐glucosidase ...
Duxuan Liu, Jing Hua, Haoyu Chen, Mingjie Wu, Zhiqing Mao, Zhen Yang, Xiubin Xu, Yanhong Hua, Chenwei Feng, Kun Zhang, Jiahuan Chen   +10 more
wiley   +1 more source

Cytotoxic Activity and Composition of Petroleum Ether Extract from Magydaris tomentosa (Desf.) W. D. J. Koch (Apiaceae)

Molecules, 2015
The petroleum ether extract of Magydaris tomentosa flowers (Desf.) W. D. J. Koch has been analyzed by GC-MS. It is mainly constituted by furanocoumarins such as xanthotoxin, xanthotoxol, isopimpinellin, and bergaptene.
Giuseppina Autore, Stefania Marzocco, Carmen Formisano, Maurizio Bruno, Sergio Rosselli, Mariem Ben Jemia, Felice Senatore   +6 more
doaj   +1 more source

Characterization of Furanocoumarin Profile and Inheritance Toward Selection of Low Furanocoumarin Seedless Grapefruit Cultivars [PDF]

Journal of the American Society for Horticultural Science, 2011
Furanocoumarins are organic chemical components in grapefruit ( Citrus paradisi ) juice that have been shown to induce potentially deleterious drug interactions. In this study we measured seven furanocoumarins (FCs) [bergamottin, 6′,7′-dihydroxybergamottin (6,7-DHB), paradisin C, bergaptol ...
Chunxian Chen, Paul Cancalon, Carl Haun, Fred Gmitter   +3 more
openaire   +1 more source

An Early Record of Photochemotherapy for Vitiligo by Rhazes (865–925 ce) in Liber Continens

JEADV Clinical Practice, EarlyView.
Alireza Tavakkoli
wiley   +1 more source

A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice–felodipine interaction [PDF]

The American Journal of Clinical Nutrition, 2006
Grapefruit juice (GFJ) enhances the systemic exposure of numerous CYP3A4 drug substrates, including felodipine, by inhibiting intestinal (but not hepatic) first-pass metabolism. Furanocoumarins have been identified as major CYP3A4 inhibitors contained in the juice, but their contribution to the GFJ effect in vivo remains unclear.To ascertain whether ...
Mary F, Paine, Wilbur W, Widmer, Heather L, Hart, Susan N, Pusek, Kimberly L, Beavers, Anne B, Criss, Sherri S, Brown, Brian F, Thomas, Paul B, Watkins   +8 more
openaire   +2 more sources

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Bidirectional Regulation of NLRP3 Inflammasome and Mitochondrial Quality Control in Sepsis: Mechanisms and Therapeutic Implications

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao, Yixun Wang, Zhaohui Zhang, Xingguang Qu, Gaosheng Zhou, Laurent L′homme   +5 more
wiley   +1 more source

Linear furanocoumarins: Bridging natural wisdom and synthetic ingenuity in drug discovery

Phytomedicine Plus
Coumarins, renowned for their adaptability and therapeutic potential, have emerged as a cornerstone in modern drug development. Nature contains these products, and scientists synthesize them in the lab, in addition to having a simple structure that can ...
Duha Adnan Hassan, Yasser Fakri Mustafa
doaj   +1 more source