Results 1 to 10 of about 28,655 (201)

Site-specific Cleavage of BMP4 by Furin, PC6, and PC7 [PDF]

, 2009
Sylvia Nelsen, Jan L. Christian
openalex   +1 more source

Ex vivo Drosophila Wing Imaginal Disc Culture and Furin Inhibitor Assay

Bio-Protocol, 2019
Furin is an evolutionarily conserved proprotein convertase (PC) family enzyme with a broad range of substrates that are essential for developmental, homeostatic, and disease pathways.
Alex Sohr, Lijuan Du, Sougata Roy
doaj   +1 more source

Furin-mediated Cleavage of Pseudomonas Exotoxin-derived Chimeric Toxins [PDF]

, 1997
Marielle F. Chiron, Charlotte M. Fryling, David Fitzgerald   +2 more
openalex   +1 more source

Fringe-positive Golgi outposts unite temporal Furin 2 convertase activity and spatial Delta signal to promote dendritic branch retraction [PDF]

, 2022
Hsun Li, Hsin-Ho Sung, Yi‐Chun Huang, Ying-Ju Cheng, Hsiao-Fong Yeh, Haiwei Pi, Edward Giniger, Cheng‐Ting Chien   +7 more
openalex   +1 more source

Effect of iron overload on furin expression in wild-type and β-thalassemic mice

Toxicology Reports, 2015
Furin is a proprotein convertase enzyme. In the liver, it cleaves prohepcidin to form active hepcidin-25, which regulates systemic iron homeostasis. Hepcidin deficiency is a component of several iron overload disorders, including β-thalassemia.
Surasak Wichaiyo, Paranee Yatmark, Ronald Enrique Morales Vargas, Pimtip Sanvarinda, Saovaros Svasti, Suthat Fucharoen, Noppawan Phumala Morales   +6 more
doaj   +1 more source

On-going evidence on SARS-CoV-2 furin site arginine codon usage bias and new found PRRA-like insertions [PDF]

, 2023
Antonio R. Romeu
openalex   +1 more source

Proprotein-processing Endoprotease Furin Decreases Regulated Secretory Pathway-specific Proteins in the Pancreatic β Cell Line MIN6 [PDF]

, 1996
Tsuyoshi Kayo, Yoshie Sawada, Yoko Suzuki, Masayuki Suda, Shigeyasu Tanaka, Yoshitaka Konda, Jun‐ichi Miyazaki, Toshiyuki Takeuchi   +7 more
openalex   +1 more source

Antibody Response to the Furin Cleavable Twenty-Seven Amino Acid Peptide (p27) of the Fusion Protein in Respiratory Syncytial Virus (RSV) Infected Adult Hematopoietic Cell Transplant (HCT) Recipients [PDF]

, 2020
Xunyan Ye, Wanderson Rezende, Obinna P. Iwuchukwu, Vasanthi Avadhanula, Laura Ferlic‐Stark, Kirtida Patel, Felipe-Andres Piedra, Dimpy P. Shah, Roy F. Chemaly, Pedro A. Piedra   +9 more
openalex   +1 more source

Proprotein Convertase FURIN Constrains Th2 Differentiation and Is Critical for Host Resistance against Toxoplasma gondii [PDF]

, 2014
Anna Oksanen, Saara Aittomäki, Dragana Janković, Zsuzsanna Ortutay, Kati Pulkkinen, Sanna Hämäläinen, Anne Rokka, Garry L. Corthals, Wendy T. Watford, Ilkka Junttila, John J. O’Shea, Marko Pesu   +11 more
openalex   +1 more source

Kallikrein-8 mediates furin-independent Activin-A precursor processing to stimulate tumor growth in melanoma

Nature Communications
Receptor binding of TGF-β and related ligands such as Activin-A requires cleavage of a furin site in their dimeric precursor proteins. Melanoma cells cleave one Activin-A subunit independently of furin and related proprotein convertases, raising ...
Manon Bulliard, Katarina Pinjusic, Laura Iacobucci, Céline Schmuziger, Nadine Fournier, Daniel B. Constam   +5 more
doaj   +1 more source