Complexity-Building ESIPT-Assisted Synthesis of Fused Polyheterocyclic Sulfonamides [PDF]
Molecules, 2023 Excited State Intramolecular Proton Transfer (ESIPT), originally discovered and explored in depth in a number of extensive photophysical studies, is more recently rediscovered as a powerful synthetic tool, offering rapid access to complex ...
Srinivas Beduru, Andrei G. Kutateladze
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Synthetic routes to benzimidazole-based fused polyheterocycles [PDF]
ARKIVOC, 2010 The review article represents a survey covering the synthetic strategies leading to benzimidazole- based fused polyheterocyclic systems utilizing simple reactive benzimidazole synthons since 1980.
Kamal M. Dawood, Bakr F. Abdel-Wahab
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Green Synthesis and Catalysis, 2023 Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang +4 more
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Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils [PDF]
Journal of Organic Chemistry, 2020 A BF3·OEt2 catalyzed intramolecular Povarov reaction was used to synthesize 15 chromenopyridine fused thiazolino-2-pyridone peptidomimetics. The reaction works with several O-alkylated salicylaldehydes and amino functionalized thiazolino-2-pyridones, to ...
Mohit Tyagi +2 more
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Rhodium catalyzed cascade cyclization featuring B–H and C–H activation: one-step construction of carborane-fused N-polyheterocycles [PDF]
Chemical Science, 2018 A novel Rh-catalyzed cascade cyclization featuring both carboranyl B–H and aryl C–H activation has been developed, resulting in the one-pot construction of three new B–C and C–C bonds.
Yangjian Quan, Zuowei Xie
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Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles. [PDF]
J Org Chem, 2019 Here we describe a facile, tandem synthetic route for indolo[3,2-c]quinolinones, a class of natural alkaloid analogues of high biological significance. A Ugi four-component reaction with indole-2-carboxylic acid and an aniline followed by a Pd-catalyzed ...
Wang Q +6 more
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Palladium‐Catalyzed Dual Csp2─Csp3 Bond Formation: A Versatile Platform for the Synthesis of Benzo‐Fused Heterocycles [PDF]
Advanced ScienceTransition‐metal‐catalyzed transformations offer a powerful approach to rapidly synthesize complex benzo‐fused heterocycles, crucial for drug and material development.
Jiahui Huang +9 more
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Chemical Communications, 2018 An unprecedented palladium-catalyzed carbene/alkyne metathesis reaction of alkyne-tethered enynones is described, which delivers fused-furans in moderate to good yields.
Yang Zheng, Ruwei Yao, Xinfang Xu
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Diverse Synthesis of Fused Polyheterocyclic Compounds via [3 + 2] Cycloaddition of In Situ-Generated Heteroaromatic N-Ylides and Electron-Deficient Olefins [PDF]
Molecules, 2023 [3 + 2] Cycloaddition reactions of heteroaromatic N-ylides with electron-deficient olefins have been developed. The heteroaromatic N-ylides, in situ generated from N-phenacylbenzothiazolium bromides, can smoothly react with maleimides under very mild ...
Zhen-Hua Wang +7 more
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Correction to Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles. [PDF]
J Org Chem, 2020 Wang Q +6 more
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