Results 11 to 20 of about 281,828 (139)

2‐Aminoindoles and 2‐Iminoindolines as Viable Precursors of Indole‐fused Nitrogenated Polyheterocycles.

Advanced Synthesis & Catalysis
The synthesis of architecturally complex polyheterocyclic structures embedding the indole ring represents a growing field of interest. Carbolines and their partially dehydro derivatives, pyrazinoindoles, indoloindoles, azepinoindoles and other medium ...
Marino Petrini
semanticscholar   +5 more sources

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades. [PDF]

J Am Chem Soc, 2021
Structurally complex benzo- and spiro-fused N-polyheterocycles can be accessed via intramolecular Pd(0)-catalyzed alkene 1,2-aminoarylation reactions. The method uses N-(pentafluorobenzoyloxy)carbamates as the initiating motif, and this allows aza-Heck ...
Jones BT, García-Cárceles J, Caiger L, Hazelden IR, Lewis RJ, Lewis RJ, Langer T, Bower JF.   +7 more
europepmc   +4 more sources

Ring Reconstruction on a Trichalcogenasumanene Buckybowl: A Facile Approach to Donor–Acceptor‐Type [5‐6‐7] Fused Planar Polyheterocycles

Angewandte Chemie - International Edition, 2015
AbstractThe transformation of trichalcogenasumanene buckybowls into donor–acceptor‐type [5‐6‐7] fused polyheterocycles is disclosed. The strategy involves a highly efficient ring‐opening of the flanking benzene upon oxidation at room temperature, and facile ring closure by functional‐group transformation.
Xuexiang Li, Shangxi Zhang, Yongliang Shao   +2 more
exaly   +5 more sources

Mo-Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties. [PDF]

Chemistry, 2021
A catalytic domino reduction–imine formation–intramolecular cyclization–oxidation for the general synthesis of a wide variety of biologically relevant N‐polyheterocycles, such as quinoxaline‐ and quinoline‐fused derivatives, and phenanthridines, is ...
Hernández-Ruiz R, Rubio-Presa R, Suárez-Pantiga S, Pedrosa MR, Fernández-Rodríguez MA, Tapia MJ, Sanz R.   +6 more
europepmc   +4 more sources

6-Exo-dig cyclization/dearomatization cascade towards N–O fused spiro polyheterocycles

Organic Chemistry Frontiers, 2023
Herein, we present a metal-free cascade cyclization of alkyne-tethered N-alkoxybenzamides for the construction of structurally novel polyheterocycles.
Erik V Van Der Eycken, Lingchao Cai, Liangliang Song   +2 more
exaly   +3 more sources

Phenanthridine-Fused Tetracyclic Ring System: Metal-Free Diastereoselective Modular Construction of Highly Constrained Polyheterocycles via Post-Ugi Tandem Modifications.

Organic Letters, 2019
A metal-free diastereo-/regioselective modular synthetic approach for the synthesis of highly constrained tetrahydroquinoline-fused tetracyclic heterocycles from easily available substrates has been developed.
K. Singh, B. Malviya, P. K. Jaiswal, V. P. Verma, S. Chimni, Siddhartha Sharma   +5 more
semanticscholar   +4 more sources

Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds [PDF]

SynOpen, 2022
The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest.
Shabber Mohammed, Jason S. West, Mark J. Mitton-Fry   +2 more
doaj   +2 more sources

Synthesis and conformational analysis of novel naphthoxazine-fused polyheterocycles [PDF]

, 2018
Barta Petra
semanticscholar   +4 more sources

Metal Coordination-Induced Electronic Tuning in Fused Polyheterocycles: Synthesis and Characterization of Cu, Zn and Fe Complexes of Benzo[a]furo[2,3-c]phenazine, Furo[3′,2′:3,4]naphtho[1,2-d]imidazole and Naphtho[1,2-b]furan-4,5-dione

Chemistry
We report the synthesis, characterisation and electronic modulation of three novel fused polyheterocyclic ligands—naphtho[1,2-b]furan-4,5-dione (1), furo[3′,2′:3,4]naphtho[1,2-d]imidazole (2), and benzo[a]furo[2,3-c]phenazine (3)—and their Cu(II), Zn(II)
Zoltán Köntös, Máté Varga
doaj   +2 more sources

Rhodium‐Catalyzed Cascade Reactions of Indoles with 4‐Hydroxy‐2‐Alkynoates for the Synthesis of Indole‐Fused Polyheterocycles

Advanced Synthesis & Catalysis, 2020
. Herein, an efficient and regioselective Rh(III)- catalyzed [4+2] annulation/lactonization cascade of indoles with 4-hydroxy-2-alkynoates at room temperature to access the furo[3',4':4,5]pyrimido[1,6-a]indole-1,5(3 H ,4 H )-diones is described.
Xiaowei Wu, Pinyi Li, Yangbin Lu, Jin Qiao, Jingwei Zhao, Xiuwen Jia, Hangcheng Ni, Li-Chun Kong, Xiaoning Zhang, Zhao Fei   +9 more
semanticscholar   +4 more sources