Identification of amino acids recognized by syncytium-inhibiting and neutralizing monoclonal antibodies to the human parainfluenza type 3 virus fusion protein [PDF]
, 1989 Kathleen Van Wyke Coelingh, E L Tierney
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
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A plasmid vector for simultaneous generation of lacZ protein fusions and npt-II operon fusions in vivo [PDF]
, 1987 Hannu LÃ¥ng +4 more
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Molecular Oncology, Volume 19, Issue 5, Page 1436-1451, May 2025.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
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Immobilization and purification of enzymes with staphylococcal protein A gene fusion vectors.
, 1985 Björn Nilsson +2 more
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Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
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Secretion of foreign proteins from Saccharomyces cerevisiae directed by alpha-factor gene fusions.
, 1984 Grant A. Bitter +3 more
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Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions [PDF]
, 1993 Dana Boyd, Beth Traxler, Jon Beckwith
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Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
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Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells.
, 1988 Clay B. Siegall +3 more
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