Results 271 to 280 of about 1,121,449 (385)

Protein targeting towards the thylakoid lumen of chloroplasts: proper localization of fusion proteins is only observed in vivo. [PDF]

, 1991
Douwe de Boer, Hans Bakker, Alice Lever, Tjeerd J. Bouma, Elma M. J. Salentijn, Peter Weisbeek   +5 more
openalex   +1 more source

Fusion Proteins for Structural Biology

, 2021
openaire   +3 more sources

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, Volume 15, Issue 5, Page 867-884, May 2025.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

Enhanced Immunogenicity of Chicken H9N2 Influenza Inactivated Vaccine Through a Novel Dual-Targeting Fusion Protein Strategy. [PDF]

Vaccines (Basel)
Xu H, Deng B, Wu E, Zhu Y, Qi Q, Feng Y, Lu Y.   +6 more
europepmc   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, Volume 15, Issue 5, Page 699-713, May 2025.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms. [PDF]

Elife
Wang Q, Liu J, Luo Y, Kliemke V, Matta GL, Wang J, Liu Q.   +6 more
europepmc   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, Volume 15, Issue 5, Page 738-753, May 2025.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Cytokine/Antibody Fusion Protein Design and Evaluation. [PDF]

Curr Protoc
Fabilane CS, Stephenson AC, Leonard EK, VanDyke D, Spangler JB.   +4 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Hyperphosphorylated tau targeting human serum albumin Fusion protein as therapeutics for Alzheimer's diseases. [PDF]

IBRO Neurosci Rep
Bang S, Song JK, Lee KH.
europepmc   +1 more source