Results 341 to 350 of about 7,331,516 (404)

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Intranasal spike and nucleoprotein fusion protein-based vaccine provides cross-protection and reduced transmission against SARS-CoV-2 variants. [PDF]

NPJ Vaccines
Lakhrif Z, Poupée-Beaugé A, Boursin F, Ducournau C, Lantier L, Moiré N, Carpentier R, Rossignol C, Maquart M, Jospin F, Merat L, Caul-Futy M, Yazdanpanah Y, Bouakane A, Riou M, Touzé A, Eléouët JF, Richard CA, Helle F, Le Poder S, Klonjkowski B, Meunier N, Zientara S, Paul S, Mévélec MN, Aubrey N, Epardaud M, Dimier-Poisson I.   +27 more
europepmc   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

FUS::DDIT3 Fusion Protein in the Development of Myxoid Liposarcoma and Possible Implications for Therapy. [PDF]

Biomolecules
Hou X, Shi W, Luo W, Luo Y, Huang X, Li J, Ji N, Chen Q.   +7 more
europepmc   +1 more source

Artificial intelligence in fusion protein three-dimensional structure prediction: Review and perspective. [PDF]

Clin Transl Med
Kumar H, Kim P.
europepmc   +1 more source

Critical domains for NACC2-NTRK2 fusion protein activation. [PDF]

PLoS One
Yang W, Meyer AN, Jiang Z, Jiang X, Donoghue DJ.   +4 more
europepmc   +1 more source

Expression of an epidermal growth factor-transdermal peptide fusion protein in <i>Arabidopsis thaliana</i> and its therapeutic effects on skin barrier repair. [PDF]

Front Plant Sci
Yu G, Lin S, Huang X, Gao S, Song C, Khalilov F, Chen Q, Issaro N, Xiao J, Xu X, Wang J, Zhao W, Wang Y, Xu N.   +13 more
europepmc   +1 more source

Amino acid changes accumulated in the fusion protein allow neuropathogenic measles viruses to use a broad repertoire of host factors for cell fusion triggering. [PDF]

J Virol
Hirai Y, Takemoto R, Yanagi Y, Shirogane Y.   +3 more
europepmc   +1 more source

Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies. [PDF]

J Virol
Schultz EP, Ponsness L, Lanchy J-M, Zehner M, Klein F, Ryckman BJ.   +5 more
europepmc   +1 more source