Results 41 to 50 of about 7,331,516 (404)

Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

Nature Communications, 2017
Nature Communications 8: Article number: 14158 (2017); Published 13 February 2017; Updated 29 November 2017. In this Article, the clinical isolate MAD/GM3_10/14 of respiratory syncytial virus (RSV) is incorrectly described as an RSV A isolate. MAD/GM3_10/
Iebe Rossey, M. Gilman, Stephanie Kabeche, Koen Sedeyn, D. Wrapp, M. Kanekiyo, Man Chen, V. Mas, J. Spitaels, J. Melero, B. Graham, Bert Schepens, J. McLellan, X. Saelens   +13 more
semanticscholar   +1 more source

Enhanced Phycocyanobilin Production in Escherichia coli by Fusion-Expression of Apo-Proteins with Signal Peptides

Fermentation, 2023
Phycocyanobilin (PCB) is the bioactive chromophore attached to Phycocyanin (PC) that is of special interest for nutraceutical and therapeutic applications. However, the production of PCB from the heterologous host Escherichia coli is still very low.
Xiaolin Liu, Jing Yu, Qian Che, Tianjiao Zhu, Dehai Li, Guojian Zhang   +5 more
doaj   +1 more source

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia

Scientific Reports, 2017
Chronic myeloid leukemia (CML) is characterized in the majority of cases by a t(9;22)(q34;q11) translocation, also called the Philadelphia chromosome, giving rise to the BCR-ABL1 fusion protein.
Liza Löf, Linda Arngården, U. Olsson‐Strömberg, Benjamin Siart, M. Jansson, Joakim S. Dahlin, I. Thörn, Lisa Christiansson, M. Hermansson, Anders Larsson, Erik Ahlstrand, Göran Wålinder, O. Söderberg, R. Rosenquist, U. Landegren, M. Kamali-Moghaddam   +15 more
semanticscholar   +1 more source

WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex [PDF]

, 2019
he formation of the fungal mycelial network is facilitated by somatic cell fusion of germinating asexual spores (or germlings). Neurospora crassa germlings in close proximity display chemotropic growth that is dependent upon an intracellular network of ...
Cea Sánchez, Sara, Chow, Karen M., Glass, N. Louise, Gonçalves, A. Pedro   +3 more
core   +2 more sources

GENOTYPING AND GENETIC EVOLUTION ANALYSIS OF NEWLY ISOLATED NEWCASTLE DISEASE VIRUS IN EGYPT

Slovenian Veterinary Research, 2021
In spite of enormous vaccination programs that were implemented in the Egyptian poultry farms, Newcastle Disease Virus (NDV) remains one of the major concerns to the poultry industry.
Yahia Madbouly, Mohammed Shakal, Eman Aly, Ashraf Hussein, Mohammed Abdelsabour, Amal Eid   +5 more
doaj   +1 more source

A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate.

New England Journal of Medicine, 1999
BACKGROUND Patients treated with methotrexate for rheumatoid arthritis often improve but continue to have active disease. This study was undertaken to determine whether the addition of etanercept, a soluble tumor necrosis factor receptor (p75):Fc fusion ...
M. Weinblatt, J. Kremer, A. Bankhurst, K. Bulpitt, R. Fleischmann, Robert I. Fox, C. G. Jackson, M. Lange, D. Burge   +8 more
semanticscholar   +1 more source

Regional perturbation of gene transcription is associated with intrachromosomal rearrangements and gene fusion transcripts in high grade ovarian cancer. [PDF]

, 2019
Genomic rearrangements are a hallmark of cancer biology and progression, allowing cells to rapidly transform through alterations in regulatory structures, changes in expression patterns, reprogramming of signaling pathways, and creation of novel ...
Beck, Tim, E Francis, Kyle, Krzyzanowski, Paul, La Rose, Jose, McPherson, John, Normand, Josee, Rottapel, Robert, Sircoulomb, Fabrice, Stein, Lincoln, Suarez, Fernando, Yousif, Fouad   +10 more
core   +2 more sources

Molecular Dynamics Simulation Reveals Exposed Residues in the Ligand-Binding Domain of the Low-Density Lipoprotein Receptor that Interacts with Vesicular Stomatitis Virus-G Envelope

Viruses, 2019
Familial hypercholesterolemia (FH) is an autosomal dominant disease most often caused by mutations in the low-density lipoprotein receptor (LDLR) gene, which consists of 18 exons spanning 45 kb and codes for a precursor protein of 860 amino acids ...
Faisal A. Al-Allaf, Zainularifeen Abduljaleel, Mohiuddin M. Taher, Ahmed A. H. Abdellatif, Mohammad Athar, Neda M. Bogari, Mohammed N. Al-Ahdal, Futwan Al-Mohanna, Zuhair N. Al-Hassnan, Kamal H. Y. Alzabeedi, Talib M. Banssir, Abdellatif Bouazzaoui   +11 more
doaj   +1 more source

An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelin

OncoImmunology, 2023
Mesothelin (MSLN) is an attractive immuno-oncology target, but the development of MSLN-targeting therapies has been impeded by tumor shedding of soluble MSLN (sMSLN), on-target off-tumor activity, and an immunosuppressive tumor microenvironment.
Daniel Snell, Tea Gunde, Stefan Warmuth, Bithi Chatterjee, Matthias Brock, Christian Hess, Maria Johansson, Alexandre Simonin, Fabio Mario Spiga, Christopher Weinert, Niels Kirk, Nicole Bassler, Lucia Campos Carrascosa, Naomi Flückiger, Robin Heiz, Sandro Wagen, Noreen Giezendanner, Alessandra Alberti, Yasemin Yaman, Dana Mahler, Dania Diem, Peter Lichtlen, David Urech   +22 more
doaj   +1 more source

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]

, 2017
Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S, Komives, Elizabeth A, Lamb, Robert A, Leser, George P, Liu, Shiheng, Salafsky, Joshua, Wong, Joyce JW, Young, Tracy A, Zhang, Jiayan, Zhou, Z Hong   +9 more
core   +2 more sources