Lectin-Fc(IgG) fusion proteins exhibit antifungal activity against the emerging multidrug-resistant pathogen Candida auris [PDF]
Infection and ImmunityCandida auris is an emerging fungal pathogen recognized among the Centers for Disease Control and Prevention’s urgent threats and designated a critical priority by the World Health Organization due to its global spread, high mortality rates, potential ...
Susana Ruiz Mendoza +7 more
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Fusion-protein-assisted protein crystallization [PDF]
Acta Crystallographica Section F Structural Biology Communications, 2015 Fusion proteins can be used directly in protein crystallization to assist crystallization in at least two different ways. In one approach, the ‘heterologous fusion-protein approach’, the fusion partner can provide additional surface area to promote ...
Kobe, Bostjan +2 more
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Viral fusion proteins of classes II and III recognize and reorganize complex biological membranes [PDF]
Communications BiologyViral infection requires stable binding of viral fusion proteins to host membranes, which contain hundreds of lipid species. The mechanisms by which fusion proteins utilize specific host lipids to drive virus–host membrane fusion remains elusive.
Chetan S. Poojari +2 more
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Comparison of antibody-scTRAIL Fc fusion proteins with varying valency for EGFR and TRAIL receptors [PDF]
Scientific ReportsFusion proteins combining TNF-related apoptosis inducing ligand (TRAIL) and antibody building blocks have emerged as a strategy for the targeted treatment of cancer cells.
Dennis Michler +3 more
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Development and evaluation of multiepitope fusion proteins for serological diagnosis of animal brucellosis [PDF]
Microbiology SpectrumBrucellosis, a zoonotic disease caused by Brucella spp., leads to severe reproductive issues in livestock and economic losses. Current serological diagnostics using lipopolysaccharide (LPS) antigens often exhibit cross-reactivity, reducing diagnostic ...
Liping Guo +9 more
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Novel Hydrophobin Fusion Tags for Plant-Produced Fusion Proteins. [PDF]
PLoS ONE, 2016 Hydrophobin fusion technology has been applied in the expression of several recombinant proteins in plants. Until now, the technology has relied exclusively on the Trichoderma reesei hydrophobin HFBI. We screened eight novel hydrophobin tags, T.
Lauri Reuter +3 more
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Editorial: Fusion proteins for the detection of pathogens or pathogen receptors [PDF]
Frontiers in Bioengineering and BiotechnologyRoger M. Benoit
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RGS1 and CREB5 are direct and common transcriptional targets of ZNF384‐fusion proteins [PDF]
Cancer MedicineBackground ZNF384‐fusion (Z‐fusion) genes were recently identified in B‐cell acute lymphoblastic leukemia (B‐ALL) and are frequent in Japanese adult patients. The frequency is about 20% in those with Philadelphia chromosome‐negative B‐ALL.
Chiharu Yamada +11 more
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Versatile toolbox for high throughput biochemical and functional studies with fluorescent fusion proteins [PDF]
, 2012 Fluorescent fusion proteins are widely used to study protein localization and interaction dynamics in living cells. However, to fully characterize proteins and to understand their function it is crucial to determine biochemical characteristics such as ...
Hake, Sandra B. +3 more
core +18 more sources
Biophysica, 2022 Bioluminescence resonance energy transfer (BRET) seems to be a promising biophysical technique to study protein–protein interactions within living cells due to a very specific reaction of bioluminescence that essentially decreases the background of other
Victor Marchenkov +4 more
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