Results 11 to 20 of about 1,010,581 (327)
Double Proteolysis for N- and O-glycan Analysis of Fc-fusion Protein Etanercept
Разработка и регистрация лекарственных средств, 2023 Introduction. Highly glycosylated proteins are the most abundant class of modern biopharmaceuticals. A majority of such therapeuticals produced by Russian biopharmaceutical companies is biosimilars.
V. G. Varzieva +4 more
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ViralFP: A Web Application of Viral Fusion Proteins
Frontiers in Medical Technology, 2021 Viral fusion proteins are attached to the membrane of enveloped viruses (a group that includes Coronaviruses, Dengue, HIV and Influenza) and catalyze fusion between the viral and host membranes, enabling the virus to insert its genetic material into the ...
Pedro Moreira +5 more
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Fusion proteins and fusion pores [PDF]
EMBO reports, 2000 Sponsored by the Juan March Foundation and organized by R D Burgoyne and G Alvarez de Toledo, Madrid, Spain, May 22–24, 2000. ![][1] A meeting was recently held at the Juan March Foundation in Madrid (22–24 May, 2000) on the topic ‘Regulated exocytosis and the vesicle cycle’.
Robert D Burgoyne +1 more
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Targeted Cytokine Delivery for Cancer Treatment: Engineering and Biological Effects
Pharmaceutics, 2023 Anti-tumor properties of several cytokines have already been investigated in multiple experiments and clinical trials. However, those studies evidenced substantial toxicities, even at low cytokine doses, and the lack of tumor specificity.
Vladislav S. Rybchenko +4 more
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Long acting growth hormone (LAGH), an update
Frontiers in Pediatrics, 2023 In 1957, Maurice Raben at Yale was able to isolate and purify growth hormone from cadaveric pituitary glands. Pituitary growth hormone was the only way to treat children with growth hormone (GH) deficiency, until 1985 when recombinant GH became available
Margaret Steiner Grillo +2 more
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eLife, 2021 Epithelioid hemangioendothelioma (EHE) is a vascular sarcoma that metastasizes early in its clinical course and lacks an effective medical therapy. The TAZ-CAMTA1 and YAP-TFE3 fusion proteins are chimeric transcription factors and initiating oncogenic ...
Nicole Merritt +11 more
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Viruses, 2023 African swine fever virus (ASFV) encodes more than 150 proteins, most of them of unknown function. We used a high-throughput proteomic analysis to elucidate the interactome of four ASFV proteins, which potentially mediate a critical step of the infection
Isabel García-Dorival +6 more
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Toxins, 2020 The deadly pandemic named COVID-19, caused by a new coronavirus (SARS-CoV-2), emerged in 2019 and is still spreading globally at a dangerous pace. As of today, there are no proven vaccines, therapies, or even strategies to fight off this virus.
Yasser Hassan, Sherry Ogg, Hui Ge
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Molecules, 2023 Oncogenic fusion proteins, arising from chromosomal rearrangements, have emerged as prominent drivers of tumorigenesis and crucial therapeutic targets in cancer research.
Yichao Kong +5 more
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Capsid-Targeted Viral Inactivation: A Novel Tactic for Inhibiting Replication in Viral Infections
Viruses, 2016 Capsid-targeted viral inactivation (CTVI), a conceptually powerful new antiviral strategy, is attracting increasing attention from researchers. Specifically, this strategy is based on fusion between the capsid protein of a virus and a crucial effector ...
Xingcui Zhang +5 more
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