Results 51 to 60 of about 60,831 (279)

Optimization of quantitative polymerase chain reactions for detection and quantification of eight periodontal bacterial pathogens [PDF]

, 2012
BACKGROUND: The aim of this study was to optimize quantitative (real-time) polymerase chain reaction (qPCR) assays for 8 major periodontal pathogens, i.e.
Cosyn, Jan, De Bruyn, Hugo, Decat, Ellen, Deschaght, Pieter, Miremadi, Seyed Reza, Saerens, Bart, Van Mechelen, Els, Vaneechoutte, Mario, Vermeulen, Stefan   +8 more
core   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Imaging characteristics and treatment of a penetrating brain injury caused by an oropharyngeal foreign body in a dog [PDF]

, 2017
A 4-year-old Border collie was presented with one episode of collapse, altered mentation, and a suspected pharyngeal stick injury. Magnetic resonance imaging (MRI) and computed tomography showed a linear foreign body penetrating the right oropharynx ...
Baroni M., Cottam EJ, Daoust PY, Dennis MM, Gennarelli TA, Ishikawa E, Jooma R, Kazim SF, Lazzerini K, Mateo I, McCandlish IA, Nishio Y, Suavé CP, Temple N, Wang HF, Zyck S   +15 more
core   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

MedZIM: Mediation analysis for Zero-Inflated Mediators with applications to microbiome data

, 2020
The human microbiome can contribute to the pathogenesis of many complex diseases such as cancer and Alzheimer's disease by mediating disease-leading causal pathways.
Christensen, Brock C., Coker, Modupe O., Datta, Susmita, Gharaibeh, Raad Z., Hoen, Anne G., Jobin, Christian, Karagas, Margaret R., Li, Zhigang, Liyanage, Janaka S. S., Madan, Juliette C., O'Malley, A. James, Wu, Quran   +11 more
core   +1 more source

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. [PDF]

, 2017
ObjectiveTo compare faecal microbial composition in patients with systemic sclerosis (SSc) from 2 independent cohorts with controls and to determine whether certain genera are associated with SSc-gastrointestinal tract (GIT) symptoms.DesignAdult patients
Braun, Jonathan, Chang, Lin, Chang, Yu-Ling, Clements, Philip J, Hoffmann-Vold, Anna-Maria, Hov, Johannes R, Jacobs, Jonathan P, Kummen, Martin, Labus, Jennifer S, Lagishetty, Venu, Mayer, Emeran A, Midtvedt, Øyvind, Molberg, Øyvind, Tillisch, Kirsten, Volkmann, Elizabeth R   +14 more
core   +1 more source

New medium selective for Fusobacterium species and differential for Fusobacterium necrophorum [PDF]

Journal of Clinical Microbiology, 1981
Fusobacterium egg yolk agar is a new medium selective for Fusobacterium species and differential for Fusobacterium necrophorum. The medium is a Brucella Agar base (Difco Laboratories, Detroit, Mich.) containing vancomycin, neomycin, josamycin, and egg yolk. All species of fusobacteria grew with only minimal inhibition. The mean log difference in counts
A A, Morgenstein, D M, Citron, S M, Finegold   +2 more
openaire   +2 more sources

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Lemierre’s syndrome: an unlikely diagnosis in a patient presenting with diarrhoea and vomiting, or maybe not?

European Journal of Case Reports in Internal Medicine
Lemierre’s syndrome is an infectious thrombophlebitis of the internal jugular vein (IJV) where the commonest causative agent is a Fusobacterium from a tonsillar or peritonsillar abscess.
Giorgos Papaleontiou, Adam Young
doaj   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source