Results 61 to 70 of about 35,069 (256)

Fusobacterium-associated molecular and immunological alterations in colorectal cancer: Insights from a Norwegian cohort

Frontiers in Immunology
BackgroundThe gut microbiome may significantly influence the development of colorectal cancer (CRC), with Fusobacterium species playing a key role. Recent research has identified Fusobacterium animalis as the predominant Fusobacterium species in CRC ...
Thura Akrem Omran, Jose Luis Subirats Camacho, Jose Luis Subirats Camacho, Thulasika Senthakumaran, Gro Gundersen, Annette Knapskog Alte, Ulla Randen, Ulla Randen, Hege Smith Tunsjø, Per Christian Sæther, Vahid Bemanian   +10 more
doaj   +1 more source

Correction: Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen

PLOS ONE
[This corrects the article DOI: 10.1371/journal.pone.0266610.].
Se Ju Lee, Yae Jee Baek, Jin Nam Kim, Ki Hyun Lee, Eun Hwa Lee, Joon Sup Yeom, Jun Yong Choi, Nam Su Ku, Jin Young Ahn, Jung Ho Kim, Su Jin Jeong   +10 more
openaire   +2 more sources

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Beyond a single species: Mapping virulence traits across the redefined Fusobacterium nucleatum complex

Virulence
Fusobacterium nucleatum was long regarded as a single species and later subdivided into four subspecies (nucleatum, polymorphum, animalis, vincentii/fusiforme).
Marietta Wolf, Konstantin J. Scholz, Ali Al-Ahmad, Thorsten Steinberg, Anne Kruse, Sama Rezasoltani, Fabian Cieplik, Georg Conrads   +7 more
doaj   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco, Nerea Maiz, Clara Franco‐Jarava, Mireia Vargas, Silvia Arévalo, María A. Sánchez‐Durán, Carlota Rodó, Manel Mendoza, Marta Dalmau, Alba Casellas, Manuel Hernández‐González, Anna Suy, María Goya   +12 more
wiley   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Anaerobic Spondylodiscitis due to Fusobacterium Species: A Case Report Review of the Literature

Case Reports in Infectious Diseases, 2015
Spondylodiscitis caused by Fusobacterium species is rare. Most cases of spontaneous spondylodiscitis are caused by Staphylococcus aureus and most postoperative cases are caused by Staphylococcus aureus or coagulase-negative staphylococci.
Tiffany N. Latta, Aimee L. Mandapat, Joseph P. Myers   +2 more
doaj   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source

Fusobacterium emphysematous pyomyositis with necrotizing fasciitis of the leg presenting as compartment syndrome: a case report

Journal of Medical Case Reports, 2017
Background Fusobacterium necrophorum is a common agent of disease in humans, but the occurrence of primary infections outside the head and neck area is extremely rare.
Eduardo Smith-Singares, Joseph Adjei Boachie, Izaskun M. Iglesias, Leland Jaffe, Adam Goldkind, Eric I. Jeng   +5 more
doaj   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source