Results 51 to 60 of about 5,149 (183)
The GalNAc-type O-Glycoproteome of CHO Cells Characterized by the SimpleCell Strategy [PDF]
, 2014 The Chinese hamster ovary cell (CHO) is the major host cell factory for recombinant production of biological therapeutics primarily because of its “human-like” glycosylation features.
Alder Schulz, Morten +12 more
core +1 more source
Aging and disease, 2023 Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease with unclear underlying molecular mechanisms and limited therapeutic options. This study aimed to explore the role of core fucosylation and the only glycosyltransferase FUT8 in PAH.
Zhang, Wen +9 more
openaire +2 more sources
Detection of differentially expressed genes between Erhualian and Large White placentas on day 75 and 90 of gestation [PDF]
, 2009 Background Placental efficiency is strongly associated with litter size, fetal weight and prenatal mortality. Together with its rapid growth during late gestation, the Large White pig breed shows a significant increase in placental size and weight, but ...
Quan-Yong Zhou +5 more
core +1 more source
Measuring facets of Worry: A LISREL analysis of the Worry Domains Questionnaire [PDF]
, 1997 In the development of the Worry Domains Questionnaire (WDQ) for the measurement of nonpathological worry, (Tallis, Eysenck & Mathews, 1992. A questionnaire for the measurement of nonpathological worry. Personality and Individual Differences, 13, 161–168)
Joormann, Jutta, Stoeber, Joachim
core +1 more source
Brain Research BulletinAlpha-(1,6)-fucosyltransferase (FUT8) has been found to play a role in modulating the central immune system and inflammatory responses. Limited studies have assessed the correlations between serum FUT8 levels and various non-motor symptoms associated ...
Qi-rong Wang +3 more
doaj +1 more source
Chinese Medical Journal, 2017 Background: Core fucosylation (CF), catalyzed by α-1,6 fucosyltransferase (Fut8) in mammals, plays an important role in pathological processes through posttranslational modification of key signaling receptor proteins, including transforming growth factor
Long-Kai Li +8 more
doaj +1 more source
Breast Cancer Research, 2022 Background We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming growth factor-β receptor enhances its signaling and promotes breast cancer invasion and metastasis.
Cheng-Fen Tu +3 more
doaj +1 more source
IgG glycosylation in autoimmune diseases [PDF]
, 2018 Immunoglobulin G (IgG) is the most abundant glycoprotein in human serum. All IgG subclasses have a single-conserved N-linked glycosylation site at Asn297 of the heavy chain and 10–30% of IgGs are N-glycosylated also in a Fab region.
Ewa Pocheć +3 more
core +2 more sources
Genomic structure and promoter analysis of the human 1,6-fucosyltransferase gene (FUT8) [PDF]
Glycobiology, 2000 GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase (alpha1,6FucT) catalyzes the transfer of a fucosyl moiety from GDP-fucose to the asparagine-linked GlcNAc residue of complex N-glycans via alpha1,6-linkage. We have cloned the genomic DNA which encodes the human alpha1,6FucT gene ( FUT8 ) and analyzed its structure.
Y, Yamaguchi +10 more
openaire +2 more sources
Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells
Viruses, 2019 Hepatitis C virus (HCV) is a major cause of human chronic liver disease and hepatocellular carcinoma. Our recent studies showed that α1,6-fucosyltransferase (FUT8), a key glycosyltransferase, was the most up-regulated glycosyltransferase after the ...
Shu Li +7 more
doaj +1 more source