Results 51 to 60 of about 616 (125)

Substrate specificity of FUT8 and chemoenzymatic synthesis of core-fucosylated asymmetric N-glycans [PDF]

Organic & Biomolecular Chemistry, 2016
Based on substrate specificity of human FUT8, an efficient strategy was developed for the synthesis of core-fucosylated asymmetric N -glycans.
Calderon, Angie D, Liu, Yunpeng, Li, Xu, Wang, Xuan, Chen, Xi, Li, Lei, Wang, Peng G   +6 more
openaire   +4 more sources

Kaplan–Meier curve illustrating incidence of epileptic seizures of patients during the follow-up period, based on Fut8 expression.

, 2023
A. The incidence of epileptic seizures in epilepsy patients within 2 years between high and low Fut8 expression. B. The incidence of epileptic seizures in refractory epilepsy patients within 2 years between high and low Fut8 expression.
Zhou Zhang (197948), Yunxiu Huang (15285530), Linmu Chen (14439559)   +2 more
core   +1 more source

MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8

Scientific Reports, 2014
In this study we investigated the biological role and mechanism of miR-198 in colorectal carcinoma (CRC). MiR-198 expression was shown to exhibit a strongly negative correlation with lymph node invasion, distant metastasis and patient survival in ...
Minyu Wang, Jilin Wang, Xuan Kong, Huimin Chen, Yingchao Wang, Miao Qin, Yanwei Lin, Haoyan Chen, Jie Xu, Jie Hong, Ying-Xuan Chen, Weiping Zou, Jing-Yuan Fang   +12 more
doaj   +1 more source

Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

Renal Failure, 2021
Objective Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it.
Changqing Yu, Ning Yang, Weidong Wang, Xiangning Du, Qingzhu Tang, Hongli Lin, Longkai Li   +6 more
doaj   +1 more source

Fut8 expression is increased in HCC tumor tissues.

, 2014
(A) The Fut8 mRNA levels were evaluated in HCC tumor tissue compared normal liver tissue from the same patients (n = 24 ...
Ruey-Hwang Chou (151749), Chen-Shiou Wu (151743), Teng-Yu Lee (577708), Yung-Luen Yu (151763), Chia-Jui Yen (151746), Chung-Yi Wu (151759), Wei-Chien Huang (151754)   +6 more
core   +1 more source

Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL

Oncogenesis
Diffuse large B-cell lymphoma (DLBCL) is characterized by its aggressive nature and resistance to standard chemotherapy, necessitating the development of new therapeutic approaches. The emergence of natural products and their derivatives has notably influenced cancer treatment, making morusinol, a medicine-derived monomer, a promising candidate.
Hao Xu, Qi Li, Yuchen Zhang, Chuan He, Xinyun Zhang, Zhiming Wang, Meifang Zhao, Yali Chai, Wenzhuo Zhuang, Bingzong Li   +9 more
openaire   +3 more sources

Intron positions shared by S. frugiperda fut8 (inumberl) and with fut8 genes identified in chordata (inumberc).

, 2014
IS: Intronic Sequence.(X): Presence of lepidopteran intron insertion site.(+): Presence of chordata intron insertion site.(*) The gene is truncated and the 5′ exon is missing.Intron positions shared by S.
François Monjaret (647590), Sylvie Juliant (647588), Marie-Luce Violet (647592), Anne Harduin-Lepers (647589), Martine Duonor-Cérutti (647595), Annick Ozil (647594), Béatrice Catieau (647591), Pierre Cérutti (647593)   +7 more
core   +1 more source

Altered mRNA Expression of Fucosyltransferases and Fucosidase Predicts Prognosis in Human Oral Carcinoma [PDF]

International Journal of Molecular and Cellular Medicine, 2021
Aberrant protein glycosylation is known to be associated with the development of various cancers. Although fucosylation is essential for normal biological functions, alterations in fucosylation are strongly implicated in cancer and increasing metastatic ...
Kruti Mehta, Kinjal Patel, Shashank Pandya, Prabhudas Patel   +3 more
doaj  

Clinicopathological characteristics of colorectal cancer patients according to FUT8 expression.

, 2018
Clinicopathological characteristics of colorectal cancer patients according to FUT8 expression.
Hirokazu Okayama (727077), Tomoyuki Momma (5485286), Masaru Noda (1595053), Shotaro Fujita (5485268), Motonobu Saito (237122), Shinji Ohki (5485292), Wataru Sakamoto (214289), Keita Aoto (5485271), Hisahito Endo (5485280), Shun Chida (5485289), Takeshi Tada (5485277), Takahiro Nakajima (61561), Mai Ashizawa (5485274), Katsuharu Saito (197101), Koji Kono (142779), Yasuhide Kofunato (5485295), Tomohiro Kikuchi (5485283)   +16 more
core   +1 more source

One-Step Enrichment of Intact Glycopeptides From Glycoengineered Chinese Hamster Ovary Cells

Frontiers in Chemistry, 2020
Recently, the glycoproteomic analysis of intact glycopeptides has emerged as an effective approach to decipher the glycan modifications of glycoproteins at the site-specific level.
Ganglong Yang, Naseruddin Höti, Shao-Yung Chen, Shao-Yung Chen, Yangying Zhou, Qiong Wang, Michael Betenbaugh, Hui Zhang, Hui Zhang   +8 more
doaj   +1 more source