Results 71 to 80 of about 5,149 (183)

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

Veterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling, Elisa Peh, Hilke Oltmanns, Jessica Meissner, Sophie Kittler, Christina Puff, Jutta Verspohl, Mathias Müsken, Madeleine Plötz, Andrea Vanessa Volk   +9 more
wiley   +1 more source

Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation

Frontiers in Immunology, 2018
CD4+ T cell activation promotes the pathogenic process of systemic lupus erythematosus (SLE). T cell receptor (TCR) complex are highly core fucosylated glycoproteins, which play important roles in T cell activation.
Wei Liang, Shanshan Mao, Shijie Sun, Ming Li, Zhi Li, Rui Yu, Tonghui Ma, Jianguo Gu, Jianing Zhang, Naoyuki Taniguchi, Wenzhe Li   +10 more
doaj   +1 more source

Clinical utility of serum fucosylated hemopexin in Japanese patients with hepatocellular carcinoma [PDF]

, 2012
Aim: Hepatocellular carcinoma (HCC) is a common clinical problem all over the world. Fucosylated hemopexin (Fuc-Hpx) is a newly reported glycoprotein for the diagnosis of HCC, however, its clinical implications are unclear.
Amano, Blomme, Bruix, Callewaert, Colombo, Comunale, Comunale, Davila, Debruyne, Delanghe, Gomaa, Jemal, Kobayashi, Liu, Liu, Llovet, Makuuchi, Miyaaki, Moriwaki, Nakagawa, Nakamura, Noda, Nouso, Nouso, Okuyama, Ruhaak, Tada, Tsutomu, Venook, Wang   +29 more
core   +1 more source

Randomised, Double‐Blinded, Placebo‐Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions

Veterinary Dermatology, Volume 37, Issue 2, Page 247-256, April 2026.
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Evi I. Sofou, Elisa Samuel, Svetlina Aleksandrova, Manolis Chatzis, Manolis N. Saridomichelakis   +4 more
wiley   +1 more source

Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons [PDF]

, 2016
Postnatal maturation of the neurons whose main phenotype and basic synaptic contacts are already established includes neuronal growth, refinement of synaptic contacts, final steps of differentiation, programmed cell death period (PCD) etc.
Jaan ePalgi, Maria eLehtivaara, Mikk eRaba, Urmas eArumäe, Urmas eArumäe   +4 more
core   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, Volume 13, Issue 8, 9 February 2026.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas. [PDF]

, 2016
Angioimmunoblastic T-cell lymphoma (AITL) and other lymphomas derived from follicular T-helper cells (TFH) represent a large proportion of peripheral T-cell lymphomas (PTCLs) with poorly understood pathogenesis and unfavorable treatment results.
Bernard, Olivier, Bisig, Bettina, Bonnet, Christophe, Bruneau, Julie, De Leval, Laurence, Delorenzi, Mauro, Dobay, Maria Pamela D, Dobay, P., Fabiani, Antoine, Fabiani, B., Fataccioli, Virginie, Figeac, Martin, Gascoyne, Randy D, Gaulard, Philippe, Grewal, Jasleen, Haioun, Corinne, Iwaszkiewicz, Justyna, Jais, Philippe, Juilland, Mélanie, Lemonnier, François, Martin, A., Michielin, Olivier, Missiaglia, Edoardo, Morin, Ryan D, Roberti, Annalisa, Thome, Margot, Tournilhac, Olivier, Vallois, David   +27 more
core   +3 more sources

MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8

Scientific Reports, 2014
In this study we investigated the biological role and mechanism of miR-198 in colorectal carcinoma (CRC). MiR-198 expression was shown to exhibit a strongly negative correlation with lymph node invasion, distant metastasis and patient survival in ...
Minyu Wang, Jilin Wang, Xuan Kong, Huimin Chen, Yingchao Wang, Miao Qin, Yanwei Lin, Haoyan Chen, Jie Xu, Jie Hong, Ying-Xuan Chen, Weiping Zou, Jing-Yuan Fang   +12 more
doaj   +1 more source

Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression

Renal Failure, 2021
Objective Peritoneal fibrosis (PF) ultimately causes ultrafiltration failure and peritoneal dialysis (PD) termination, but there are few effective therapies for it.
Changqing Yu, Ning Yang, Weidong Wang, Xiangning Du, Qingzhu Tang, Hongli Lin, Longkai Li   +6 more
doaj   +1 more source

Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]

, 2015
Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core   +1 more source