Results 1 to 10 of about 3,592,863 (264)

Structural comparison of unconventional G protein YchF with heterotrimeric G protein and small G protein [PDF]

open access: yesPlant Signaling & Behavior, 2022
Guanine nucleotide-binding (G) proteins, namely, phosphate-binding (P) loop GTPases, play a critical role in life processes among different species. Based on the structural characteristics, G proteins can be divided into heterotrimeric G proteins, small ...
Maozhen Luo   +7 more
doaj   +3 more sources

Oliceridine- Opioid of the 21st Century

open access: yesSaudi Journal of Anaesthesia, 2022
Oliceridine (Olinvyk® Trevena, PA, USA) was approved by the United States Food and Drug Administration for clinical use on Aug 8, 2020. Even though, the indication of its approval is very restrictive (to manage moderate-to-severe acute pain in adults ...
Basavana Goudra
doaj   +1 more source

Comprehensive Transcriptome Analysis of GS3 Near-Isogenic Lines During Panicle Development in Rice (Oryza sativa L.)

open access: yesFrontiers in Genetics, 2022
Panicle architecture is an important agronomic trait in rice that affects rice yields and quality. The GRAIN SIZE 3 (GS3) locus has been identified as a major quantitative trait locus (QTL) affecting grain length and weight.
Wenhua Liang   +13 more
doaj   +1 more source

BSA nanoparticles loaded with IONPs for biomedical applications: fabrication optimization, physicochemical characterization and biocompatibility evaluation [PDF]

open access: yesNanomedicine Journal, 2019
Objective(s): Cancer diagnosis in its early stages of progress, can enhance the efficiency of treatment utilizing conventional therapy methods. Non-biocompatibility of iron oxide nanoparticles (IONPs) has made a big challenge against their usage as a ...
Parvin Najafi, Hasan Kouchakzadeh
doaj   +1 more source

Structure-Guided Designing and Evaluation of Peptides Targeting Bacterial Transcription

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The mycobacterial RNA polymerase (RNAP) is an essential and validated drug target for developing antibacterial drugs. The β-subunit of Mycobacterium tuberculosis (Mtb) RNAP (RpoB) interacts with an essential and global transcription factor, CarD, and ...
Gundeep Kaur   +4 more
doaj   +1 more source

The Evolution of Intein-Based Affinity Methods as Reflected in 30 years of Patent History

open access: yesFrontiers in Molecular Biosciences, 2022
Self-cleaving affinity tags, based on engineered intein protein domains, have been touted as a universal single step purification platform for tagless non-mAb proteins.
Sai Vivek Prabhala   +3 more
doaj   +1 more source

Effects of propofol on β-adrenoceptor-mediated signal transduction in cardiac muscle; role of cAMP [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
BackgroundPropofol may decrease myocardial contractility via actions on the β-adrenoceptor-mediated signal transduction. The aim of this study was to evaluate the effect of propofol via β-adrenoceptor-mediated signal transduction by measuring the tissue ...
Chul Ho Chang, Go Un Roh, Wyun Kon Park
doaj   +1 more source

Transforming G proteins [PDF]

open access: yesOncogene, 2001
Heterotrimeric guanine nucleotide binding proteins, commonly known as G proteins form a super-family of signal transduction proteins. They are peripherally associated with the plasma membrane and provide signal coupling to seven transmembrane surface receptors. G proteins are composed of monomers of alpha, beta, and gamma subunits.
V, Radhika, N, Dhanasekaran
openaire   +2 more sources

Obtaining and Characterization of the Monoclonal Antibodies Against G-Protein of the Respiratory Syncytial Virus

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2020
The aim of this study was to obtain hybridomas producing monoclonal antibodies (Mabs) to the G-protein of the respiratory syncytial virus (RSV), and to evaluate their immunological characteristics and virus-neutralizing activity.Material and methods ...
N. A. Demidova   +8 more
doaj   +1 more source

Structure Elucidation and Biochemical Characterization of Environmentally Relevant Novel Extradiol Dioxygenases Discovered by a Functional Metagenomics Approach

open access: yesmSystems, 2019
The release of synthetic chemical pollutants in the environment is posing serious health risks. Enzymes, including oxygenases, play a crucial role in xenobiotic degradation. In the present study, we employed a functional metagenomics approach to overcome
Chandni Sidhu   +3 more
doaj   +3 more sources

Home - About - Disclaimer - Privacy