Results 91 to 100 of about 503,639 (262)

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Proceedings of the National Academy of Sciences of the United States of America, 2007
Blaine N. Armbruster, Xiang Li, M. Pausch, S. Herlitze, B. Roth   +4 more
semanticscholar   +1 more source

Extensive proteolysis inhibits high-level production of eukaryal G protein-coupled receptors in the archaeon Haloferax volcanii [PDF]

, 1999
Nadja Patenge
openalex   +1 more source

Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus [PDF]

, 1997
Nicholas Davis‐Poynter, Dona M. Lynch, Hassan Vally, G. R. Shellam, William D. Rawlinson, B. G. Barrell, Helen E. Farrell   +6 more
openalex   +1 more source

Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. [PDF]

, 1996
Martin Oppermann, Marı́a A. Diversé-Pierluissi, Mark H. Drazner, Shanny L. Dyer, Neil J. Freedman, Karsten Peppel, Robert J. Lefkowitz   +6 more
openalex   +1 more source

Whole body deletion of Gpr68 does not change hematopoietic stem cell function

Stem Cell Research, 2020
G protein-coupled receptor 68 (GPR68) responds to extracellular protons, thus called the proton-sensing G protein-coupled receptor (GPCR), leading to activation of the phospholipase C-β (PLCβ)/calcium (Ca2+) pathway or the adenylyl cyclase (AC)/cyclic ...
Xiaofei He, Caleb Hawkins, Lauren Lawley, Kennedy Freeman, Tra Mi Phan, Jiajia Zhang, Yan Xu, Jing Fang   +7 more
doaj  

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.

, 1991
Lee F. Allen, R J Lefkowitz, M G Caron, Susanna Cotecchia   +3 more
openalex   +1 more source

Regulation of the G-Protein-Coupled α-Factor Pheromone Receptor by Phosphorylation [PDF]

, 1996
Qijun Chen, James B. Konopka
openalex   +1 more source

Inhibition of thrombin receptor signaling by a G-protein coupled receptor kinase. Functional specificity among G-protein coupled receptor kinases.

, 1994
Kenji Ishii, J. Chen, Maki Ishii, Walter J. Koch, Neil J. Freedman, R J Lefkowitz, Shaun R. Coughlin   +6 more
openalex   +1 more source

Deep Learning Dynamic Allostery of G‑Protein-Coupled Receptors

JACS Au, 2023
Hung N. Do, Jinan Wang, Yinglong Miao
doaj   +1 more source

Application of FRET- and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors

SLAS Discovery
Bioluminescence- and fluorescence-based resonance energy transfer assays have gained considerable attention in pharmacological research as high-throughput scalable tools applicable to drug discovery. To this end, G protein-coupled receptors represent the
Joanna J. Sajkowska, Choi Har Tsang, Paweł Kozielewicz   +2 more
doaj