Results 51 to 60 of about 14,208,503 (293)
Responsive DNA G-quadruplex micelles [PDF]
Chemical Communications, 2018 A novel design of DNA-G-quadruplex micelles is presented, which can be disassembled by addition of a complementary strand, resulting in the release of an embedded cargo.
Liliana Cozzoli +4 more
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Novel splicing in IGFN1 intron 15 and role of stable G-quadruplex in the regulation of splicing in renal cell carcinoma. [PDF]
PLoS ONE, 2018 The IGFN1 (Immunoglobulin-Like And Fibronectin Type III Domain Containing 1) gene has a role in skeletal muscle function and is also involved in metastatic breast cancer, and the isoforms with three N-terminal globular domains are sufficient for its ...
Shiv Prakash Verma, Parimal Das
doaj +1 more source
Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy
Molecules, 2019 A G-quadruplex (G4) is a well-known nucleic acid secondary structure comprising guanine-rich sequences, and has profound implications for various pharmacological and biological events, including cancers.
Sefan Asamitsu +4 more
semanticscholar +1 more source
G-Quadruplexes as Sensing Probes [PDF]
Molecules, 2013 Guanine-rich sequences of DNA are able to create tetrastranded structures known as G-quadruplexes; they are formed by the stacking of planar G-quartets composed of four guanines paired by Hoogsteen hydrogen bonding. G-quadruplexes act as ligands for metal ions and aptamers for various molecules.
Ruttkay-Nedecký, Branislav +5 more
openaire +4 more sources
PLoS ONE, 2012 Studies on ligand interaction with quadruplex DNA, and their role in stabilizing the complex at concentration prevailing under physiological condition, has attained high interest.
Gajjela Raju +5 more
doaj +1 more source
Topologies of G-quadruplex: Biological functions and regulation by ligands.
Biochemical and Biophysical Research Communications - BBRC, 2020 G-Quadruplex (G4) is one of the higher-order structures occurring in guanine-rich sequences of nucleic acids, and plays critical roles in biological processes. The G4-forming sequences can generate three kinds of topologies, i.e., parallel, anti-parallel,
Yue Ma, Keisuke Iida, K. Nagasawa
semanticscholar +1 more source
Replication of G Quadruplex DNA [PDF]
Genes, 2019 A cursory look at any textbook image of DNA replication might suggest that the complex machine that is the replisome runs smoothly along the chromosomal DNA. However, many DNA sequences can adopt non-B form secondary structures and these have the potential to impede progression of the replisome.
Leticia Koch Lerner, Julian E. Sale
openaire +2 more sources
RNA G-quadruplex structures exist and function in vivo in plants
Genome Biology, 2020 Background Guanine-rich sequences are able to form complex RNA structures termed RNA G-quadruplexes in vitro. Because of their high stability, RNA G-quadruplexes are proposed to exist in vivo and are suggested to be associated with important biological ...
Xiaofei Yang +10 more
doaj +1 more source
Advanced Sensor and Energy MaterialsG-quadruplex is a high-level structure composed of folded DNA or RNA rich in tandem repeats of guanine (G). In recent years, G-quadruplex is widely used in various fields due to its unique structural properties.
Ping Lu, Gerile Aodeng, Jun Ai
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A new cationic porphyrin derivative (TMPipEOPP) with large side arm substituents: a highly selective G-quadruplex optical probe. [PDF]
PLoS ONE, 2012 The discovery of uncommon DNA structures and speculation about their potential functions in genes has brought attention to specific DNA structure recognition.
Li-Na Zhu +4 more
doaj +1 more source