TSH Activates Macrophage Inflammation by G13- and G15-dependent Pathways [PDF]
AbstractThyroid-stimulating hormone (TSH) treatment activates inhibitor of NF-κB/nuclear factor κB (IκB/NFκB) and extracellular signal-regulated kinase (ERK)–P38 in macrophages, but how these pathways are activated, and how they contribute to the proinflammatory effect of TSH on macrophages remain unknown.
Chongbo Yang+6 more
semanticscholar +4 more sources
Detection and molecular characterization of porcine enterovirus G15 and teschovirus from India [PDF]
ABSTRACT Porcine enterovirus G (EV-G) and teschovirus (PTV) generally cause asymptomatic infections. Although both viruses have been reported from various countries, they are rarely detected from India. To detect these viruses in Western India, fecal samples (n = 26) of diarrheic piglets aged below three months from private pig farms ...
Pradeep Sawant+3 more
semanticscholar +5 more sources
Mg2+ binding and archaeosine modification stabilize the G15–C48 Levitt base pair in tRNAs [PDF]
The G15–C48 Levitt base pair, located at a crucial position in the core of canonical tRNAs, assumes a reverse Watson–Crick (RWC) geometry. By means of bioinformatics analysis and quantum mechanics calculations we show here that such a geometry is moderately more stable than an alternative bifurcated trans geometry, involving the guanine Watson–Crick ...
Romina Oliva+2 more
semanticscholar +7 more sources
The puzzling uniqueness of the heterotrimeric G15 protein and its potential beyond hematopoiesis [PDF]
Heterotrimeric G proteins transduce the signals of the largest family of membrane receptors (G protein-coupled receptors, GPCRs) hence triggering the activation of a wide variety of physiological responses. G15 is a G protein characterized by a number of functional peculiarities that make its signaling exceptional: 1) it can couple a variety of Gs-, Gi/
Flavia Giannone+13 more
semanticscholar +6 more sources
Differential temperature effect on the production of enhanced gamma linolenic acid in Mucor rouxii CFR-G15 [PDF]
Mucor rouxii CFR-G15, a locally isolated phycomycetous fungus, on cultivation at room temperature produced more than 30% (w/w) lipid in their dry cell weight, in which 14.2% accounted to be GLA content of the total fatty acids. It was observed that when incubation temperature lowered at 14°C, GLA content of the mycelium increased significantly ...
S.S. Mamatha, G. Venkateswaran
semanticscholar +6 more sources
Governance and Exports Based on Superior Technology: A Case Study of G15 Countries [PDF]
Nowadays, knowledge is more and more applied in using domestic products, pushing the boundaries of technology, and increasing its penetration in the export development strategies.
Abolfazl Shahabadi, Hanieh Samari
doaj +3 more sources
Insights into the Factors Controlling the Origin of Activation Barriers in the [2 + 2] Cycloaddition Reactions of Heavy Imine-like Molecules Featuring a Ge=Group 15 Double Bond with Heterocumulenes [PDF]
The [2 + 2] cycloaddition reactions of the heterocumulene (N=C=N) with the heavy imine-like molecule Ge=G15-Rea (G15 = Group 15 element) were examined using density functional theory (M06-2X-D3/def2-TZVP).
Zheng-Feng Zhang, Ming-Der Su
doaj +2 more sources
G15 A one year longitudinal study on effectiveness of strategies to engage ‘hard to reach ‘looked after children’: Abstract G15 Table 1 [PDF]
Guidance for Looked after Children (LAC) stipulates the requirement for detailed health assessments by specialised professionals on entry to care and regularly thereafter. However it was identified in 2012 that locally a high proportion of LAC consistently refused health assessments. Aim To conduct a needs analysis and identify if new strategies could
Stephanie Cope
openalex +2 more sources
Structural Insights into an Antiparallel Chair-Type G-Quadruplex From the Intron of NOP56 Oncogene. [PDF]
This study first reports that the intron 1 of NOP56 oncogene forms an antiparallel chair‐type G4 structure composed of two G‐tetrads and one C∙G∙C∙G tetrad. NOP56 gene transcription can be inhibited by PDS that binds and stabilizes NOP56‐G4. Solution NMR structures of the free NOP56‐G4 and NOP56‐G4‐PDS complex provide valuable insights into G4 ...
Yan Z+11 more
europepmc +2 more sources
G15(P) Paediatricians' Competence and Attitudes Towards Their Diagnostic Radiology Skills [PDF]
Aims Many clinicians find themselves self-interpreting the radiological images of their patients, especially in the acute management setting whilst on-call. The aim of this study was to assess the competence and attitudes of paediatric clinicians towards their diagnostic radiology skills.
M. Meenakshi Sundaram+2 more
openalex +3 more sources