Results 121 to 130 of about 5,954 (200)

Identification of metastasis associated gene G3BP by differential display in human cancer cell sublines with different metastatic potentials G3BP as highly expressed in non-metastatic.

Chinese medical journal, 2002
To investigate genes involved in cancer metastasis, mRNA differential display was used to compare the levels of gene expression in two cell sublines derived from human giant cell carcinoma of lung (PG) which had different metastatic potentials.Using in vivo tumorigenicity and a spontaneous metastasis assay in nude mice, two sublines (BE1, LH7) from ...
Y, Liu, J, Zheng, W, Fang, J, You, J, Wang, X, Cui, B, Wu   +6 more
openaire   +1 more source

Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform [PDF]

RIG-I is a key cytosolic RNA sensor that mediates innate immune defense against RNA virus. Aberrant RIG-I activity leads to severe pathological states such as autosomal dominant multi-system disorder, inflammatory myophathies and dermatomyositis ...
Hesung Now, Nari Kim, Nguyen Thi Hong Nhung, Woo-Jong Kim, Yoo, JY   +4 more
core   +1 more source

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Cell Reports
Summary: G3BP1/2 are paralogous proteins that promote stress granule formation in response to cellular stresses, including viral infection. The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibits stress ...
Zemin Yang, Bryan A. Johnson, Victoria A. Meliopoulos, Xiaohui Ju, Peipei Zhang, Michael P. Hughes, Jinjun Wu, Kaitlin P. Koreski, Jemma E. Clary, Ti-Cheng Chang, Gang Wu, Jeff Hixon, Jay Duffner, Kathy Wong, Rene Lemieux, Kumari G. Lokugamage, R. Elias Alvarado, Patricia A. Crocquet-Valdes, David H. Walker, Kenneth S. Plante, Jessica A. Plante, Scott C. Weaver, Hong Joo Kim, Rachel Meyers, Stacey Schultz-Cherry, Qiang Ding, Vineet D. Menachery, J. Paul Taylor   +27 more
doaj   +1 more source

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Nature Communications
Considerable progress has been made in understanding the molecular host-virus battlefield during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed virions are less understood.
Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun   +13 more
doaj   +1 more source

USP21-mediated G3BP1 stabilization accelerates proliferation and metastasis of esophageal squamous cell carcinoma via activating Wnt/β-Catenin signaling

Oncogenesis
Lacking effective therapeutic targets heavily restricts the improvement of clinical prognosis for patients diagnosed with esophageal squamous cell carcinoma (ESCC).
Jiazhong Guo, Yunpeng Zhao, Huacong Sui, Lei Liu, Fanrong Liu, Lingxiao Yang, Fengyuan Gao, Jinfu Wang, Yilin Zhu, Lingbing Li, Xiangqing Song, Peng Li, Zhongxian Tian, Peichao Li, Xiaogang Zhao   +14 more
doaj   +1 more source

Histone methyltransferase KMT2D targets the SPOP-G3BP1 axis to enhance AR stability and drive castration-resistant prostate cancer progression

Molecular Biomedicine
Castration-resistant prostate cancer (CRPC) poses a significant clinical challenge, characterized by limited therapeutic options and unfavorable prognosis, particularly among elderly men.
Haoran Wen, Maierhaba Maheremu, Kaidi Zhang, Liuru Bao, Mayao Luo, Yifan Zhang, Yuanpeng Liao, Manli Zhou, Chenwei Wu, Shidong Lv, Xiaofu Qiu, Qiang Wei   +11 more
doaj   +1 more source

Main directions of proteomic researches in breast cancer [PDF]

, 2017
В огляді особлива увага приділяється напрямам застосування протеомного аналізу з метою впровадження отриманих результатів в клінічну практику для профілактики, скринінгу, діагностики, терапії і прогнозу раку молочної залози.
Мазур, М.Г., Пятчанина, Т.В.   +1 more
core  

Rôle des protéines G3BP dans la réplication du virus SARS-CoV-2

médecine/sciences
No abstract ...
Aubé, Corentin, Murigneux, Émilie, Softic, Laurent, Judith, Delphine, Berlioz-Torrent, Clarisse, Gallois-Montbrun, Sarah   +5 more
openaire   +1 more source

The assessment of urinary Galectin-3 Binding Protein (G3BP)/creatinine ratio as a biomarker for lupus nephritis in Egyptian patients

Egyptian Rheumatology and Rehabilitation
Aim of the Study This research aims to review the clinical usefulness of the urinary Galectin-3 Binding Protein (uG3BP)/creatinine ratio in lupus nephritis (LN) patients and its relationship to disease activity to assess its utility as a biomarker for ...
Ahmed Y Ali, Dina Mahmoud, Shaimaa Mohamed Ali, Mariam A Elmohandes, Sarah A. Hassan   +4 more
doaj   +1 more source

Erratum to: Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP [PDF]

, 2015

core   +1 more source