Results 111 to 120 of about 4,644 (183)

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Nature Communications
Considerable progress has been made in understanding the molecular host-virus battlefield during SARS-CoV-2 infection. Nevertheless, the assembly and egress of newly formed virions are less understood.
Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun   +13 more
doaj   +1 more source

Site-directed mutagenesis in the FGDF peptide binding cleft of G3BP.

, 2015
(A) Schematic representation of the G3BP-F33W mutant (upper panel) and the G3BP-F124W mutant (lower panel) with the modeled LTFGDFDE peptide. The LTFGDFDE peptide is displayed as sticks with yellow carbon atoms.
Tatiana Sandalova (690366), Adnane Achour (113247), Tim Schulte (690365), Nancy Kedersha (690367), Marc D. Panas (690364), Bastian Thaa (418825), Gerald M. McInerney (250016)   +6 more
core   +1 more source

USP21-mediated G3BP1 stabilization accelerates proliferation and metastasis of esophageal squamous cell carcinoma via activating Wnt/β-Catenin signaling

Oncogenesis
Lacking effective therapeutic targets heavily restricts the improvement of clinical prognosis for patients diagnosed with esophageal squamous cell carcinoma (ESCC).
Jiazhong Guo, Yunpeng Zhao, Huacong Sui, Lei Liu, Fanrong Liu, Lingxiao Yang, Fengyuan Gao, Jinfu Wang, Yilin Zhu, Lingbing Li, Xiangqing Song, Peng Li, Zhongxian Tian, Peichao Li, Xiaogang Zhao   +14 more
doaj   +1 more source

Histone methyltransferase KMT2D targets the SPOP-G3BP1 axis to enhance AR stability and drive castration-resistant prostate cancer progression

Molecular Biomedicine
Castration-resistant prostate cancer (CRPC) poses a significant clinical challenge, characterized by limited therapeutic options and unfavorable prognosis, particularly among elderly men.
Haoran Wen, Maierhaba Maheremu, Kaidi Zhang, Liuru Bao, Mayao Luo, Yifan Zhang, Yuanpeng Liao, Manli Zhou, Chenwei Wu, Shidong Lv, Xiaofu Qiu, Qiang Wei   +11 more
doaj   +1 more source

Alphavirus-host interactions : how to unravel the proviral activity of G3BP [Elektronisk resurs]

, 2019
The genus Alphavirus belongs to the virus family Togaviridiae, a group of arthropod-borne enveloped RNA viruses with single-stranded, positive-sense genome.
Götte, B,
core  

The stress granules component G3BP : functional characterization from KO mouse and identification of its ribonucleoprotein interactome in mouse brain

, 2012
Les protéines capables de lier des ARNs sont essentielles pour les différentes étapes de maturation de l'ARN messager (ARNm), en dirigeant leur localisation et leur devenir dans la cellule, et en formant avec les ARNs des particules ribonucléoprotéiques (
Martin, Sophie
core  

The assessment of urinary Galectin-3 Binding Protein (G3BP)/creatinine ratio as a biomarker for lupus nephritis in Egyptian patients

Egyptian Rheumatology and Rehabilitation
Aim of the Study This research aims to review the clinical usefulness of the urinary Galectin-3 Binding Protein (uG3BP)/creatinine ratio in lupus nephritis (LN) patients and its relationship to disease activity to assess its utility as a biomarker for ...
Ahmed Y Ali, Dina Mahmoud, Shaimaa Mohamed Ali, Mariam A Elmohandes, Sarah A. Hassan   +4 more
doaj   +1 more source

Contribution de l'endoribonucléase G3BP dans le remodelage des particules ribonucléoprotéiques, ex vivo et in vivo, au cours du développement chez la souris

, 2006
Les mRNP subissent divers remodelages dans la cellule nécessaires à leur localisation, traduction et dégradation. Parmi les composantes de certaines mRNP cellulaire, G3BP est une endoribonucléase capable de cliver spécifiquement les ARNm.
TAZI, Jamal, ZEKRI, Latifa
core  

ASPL couples the assembly of stress granules with their VCP-mediated disassembly. [PDF]

Sci Adv
Pareek G, Li D, Wang B, Wu J, Freibaum BD, Basalla JL, Mahendran TS, Singh A, Nourse A, Quan H, Kalathur R, Rana MS, Maxwell B, Wang YD, Messing J, Ni Y, Pounds S, Dharmat R, Lu J, Li-Harms X, Carisey AF, Pruett-Miller SM, Taylor JP, Banerjee P, Kim HJ, Kundu M.   +25 more
europepmc   +1 more source

The assembly of stress granules during foot-and-mouth disease virus infection is uncoupled from activation of cellular intrinsic antiviral signalling. [PDF]

PLoS Pathog
Marques M, Wong YX, Sun Z, Yasmin A, Taylor JP, Ruggieri A, Tuthill TJ, Locker N.   +7 more
europepmc   +1 more source