Results 111 to 120 of about 5,954 (200)
, 2008 An abundantly growing body of literature implicates conjugation of SUMO in the regulation of many proteins and processes, yet the regulation of SUMO pathways is poorly understood.
Brian J Wilson
core +2 more sources
Advanced Science, Volume 12, Issue 14, April 10, 2025.In EAE mice, TIA1 is translocated from the nucleus to the cytoplasm, facilitating SGs formation in neurons. TIA1 knockout in the central nervous system (CNS) of EAE mice yields a notable diminution in neuronal SGs, mitigates CNS inflammatory infiltration, and curtails axonal demyelination.
Xin Hua +13 more
wiley +1 more source
Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases [PDF]
, 2019 The human Miro GTPases (hMiros) have recently emerged as important mediators of mitochondrial transport and may significantly contribute to the development of disorders such as Alzheimer’s and schizophrenia.
Black, Gary +3 more
core +1 more source
Frontiers in Immunology, 2018 Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation and the innate immune ...
Xu Ye +20 more
doaj +1 more source
Rasputin a decade on and more promiscuous than ever? A review of G3BPs
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2019 Ras-GTPase-activating protein (SH3 domain)-binding proteins (G3BPs, also known as Rasputin) are a family of RNA binding proteins that regulate gene expression in response to environmental stresses by controlling mRNA stability and translation. G3BPs appear to facilitate this activity through their role in stress granules for which they are considered a
Alam, Umber, Kennedy, Derek
openaire +3 more sources
A bootstrap-based regression method for comprehensive discovery of differential gene expressions: An application to the osteoporosis study [PDF]
, 2011 A common purpose of microarray experiments is to study the variation in gene expression across the categories of an experimental factor such as tissue types and drug treatments.
Deng, HW +4 more
core +1 more source
A statistical method for predicting splice variants between two groups of samples using GeneChip expression array data [PDF]
, 2006 Background: Alternative splicing of pre-messenger RNA results in RNA variants with combinations of selected exons. It is one of the essential biological functions and regulatory components in higher eukaryotic cells. Some of these variants are detectable
Fan, Wenhong +4 more
core +1 more source
Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules
Viruses, 2015 We have previously shown that poliovirus (PV) infection induces stress granule (SG) formation early in infection and then inhibits the formation of SG and disperses processing bodies (PBs) by the mid-phase of infection.
Jonathan D. Dougherty +2 more
doaj +1 more source
The eukaryotic linear motif resource - 2018 update. [PDF]
, 2018 Short linear motifs (SLiMs) are protein binding modules that play major roles in almost all cellular processes. SLiMs are short, often highly degenerate, difficult to characterize and hard to detect.
Gouw, Marc +5 more
core +1 more source
Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting [PDF]
, 2019 Sphingosine kinases 1 and 2 (SK1 and SK2) are proto-oncogenic isozymes expressed in many human tumors and associated with chemoresistance and poor prognosis.
Alshaker +30 more
core +4 more sources