Results 111 to 120 of about 1,908 (177)

Additional file 2: of Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

, 2018
Figure S1. circFNDC3B inhibits proliferation of BC cells. a and b qRT-PCR analysis for circFNDC3B and FNDC3B mRNA in UM-UC-3 cells treated with siRNAs or T24 cells transfected with circFNDC3B overexpression vector.
Junming Bi (5997452), Meihua Yang (543922), Hongwei Liu (80414), Jian Huang (7250), Juanyi Shi (5997455), Wei Dong (6479), Ning Jiang (118848), Tianxin Lin (317718)   +7 more
core   +1 more source

ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway

Discover Oncology
Clear cell renal cell carcinoma (ccRCC), with high mortality and poor prognosis, is the most common type of renal malignancy. It is necessary to identify new biomarkers that can serve as indicators for the detection of ccRCC at its early stages.
Yuming Liu, Dehua Zeng, Yunzhen Gao
doaj   +1 more source

The Role of Twist1 in Cellular Mechanosensing / [PDF]

, 2014
Mechanical forces are recently recognized as potent regulatory signals of cellular behavior in a wide range of biological contexts, including tumor progression and stem cell differentiation (Calvo et al., 2013; Dupont et al., 2011; Engler et al., 2006 ...
Wei, Spencer C.
core  

G3BP-nsP3 complexes bind viral G RNA in CHIKV-infected cells.

, 2016
(A) Colocalization of CHIKV nsP3-Cherry (pseudocolored in green) fusion proteins with CHIKV G RNA. Images are presented as MIP of 6 x-y sections (1 μm) through the middle plane of nucleus. Bars: 10 and 3 μm.
Dal Young Kim (732823), Ivan Akhrymuk (2934816), Elena I. Frolova (732826), Josephine M. Reynaud (732822), Ilya Frolov (211903), Aliaksandra Rasalouskaya (732825), James A. Mobley (365303)   +6 more
core   +1 more source

Model of the DENV-2 sfRNA antagonizing IFN action.

, 2014
IFNs are produced by infected cells and released in the extracellular space. Binding of IFN to IFNAR on neighboring naïve cells activates a cascade of signaling events leading to selective transcriptional activation of ISGs, which contain an interferon ...
Mariano A. Garcia-Blanco (136317), Dhivya Dadlani (592227), Katell Bidet (592226)   +2 more
core   +1 more source

Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP)

, 2007
Inactivation of the p53 tumor suppressor pathway is a critical step in human tumorigenesis. In addition to mutations, p53 can be functionally silenced through its increased degradation, inhibition of its transcriptional activity and/or its inappropriate ...
Kennedy, D, Kim, MM, Hansen, E, Wiederschain, D, Yuan, Z-M   +4 more
core  

Investigating the interactions between lipid membranes and G3BP2 protein condensates in vitro, and stress granules as cellular analogues of condensates, using G3BP1

V celicah se s procesom ločitve tekočih faz (LLPS) tvorijo številni nemembranski organeli. Mednje uvrščamo stresne granule, ki se v citosolu tvorijo, ko je celica izpostavljena različnim oblikam stresa.
Kodra, Ana Marija
core  

Stress Granule-Driven Resistance in Cancer: Mechanisms and Emerging Strategies. [PDF]

Cancers (Basel)
Rajendiran A, Ramakrishnan G, Ohn T, Jayabalan AK.   +3 more
europepmc   +1 more source

Pharmacological modulation of stress granules <i>via</i> G3BP1/2: A pathway to treat cancer, inflammatory disease, and neurodegeneration. [PDF]

Front Pharmacol
Yang J, Gao F.
europepmc   +1 more source

Single-granule profiling reveals that RNP granule pH marks cellular translation. [PDF]

iScience
Zhang Y, Wu S, He Y, Xia X, Wei J, Wu S, Deng R.   +6 more
europepmc   +1 more source