Results 111 to 120 of about 46,511 (206)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

G Protein-Coupled Estrogen Receptor Regulates Mesenchymal Stem Cell Mechanotransduction and Differentiation. [PDF]

Cell Mol Bioeng
Wang H, Ben Menachem-Zidon O, Pandey A, Xiao Y, Deng N, Shi X, Ruiz A, Ye Y, Cai H.   +8 more
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Sex differences in G protein-coupled estrogen receptor-mediated mechanisms in preclinical models of anxiety and fear. [PDF]

Front Behav Neurosci
Tran AS, Maeng LY.
europepmc   +1 more source

Stimulatory Anticancer Effect of Resveratrol Mediated by G Protein-Coupled Estrogen Receptor in Colorectal Cancer. [PDF]

Biomol Ther (Seoul), 2023
Kim N, Kwon J, Shin US, Jung J.
europepmc   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

G protein-coupled Estrogen Receptor Activation Exerts Protective Effects via Modulating Brain and Gut NLRP3 Inflammasome in Parkinson's Disease. [PDF]

Exp Neurobiol
Liang Y, Zhou L, Liu H, Huang X, Li Y, Li X, Huang S.   +6 more
europepmc   +1 more source

G Protein-Coupled Estrogen Receptor GPER: Molecular Pharmacology and Therapeutic Applications. [PDF]

Annu Rev Pharmacol Toxicol, 2023
Arterburn JB, Prossnitz ER.
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

G protein-coupled estrogen receptor deficiency exacerbates demyelination through microglial ferroptosis. [PDF]

J Biol Chem
Mi X, Li J, Feng Z, Liu Y, Zhang C, Shao Y, Wang T, Yang Z, Lv H, Liu J.   +9 more
europepmc   +1 more source