Results 251 to 260 of about 1,156,973 (433)

Structural basis for lipid-mediated activation of G protein-coupled receptor GPR55. [PDF]

Nat Commun
Claff T, Ebenhoch R, Kley JT, Magarkar A, Nar H, Weichert D.   +5 more
europepmc   +1 more source

G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo.

, 1996
Aki Nagata, Mitsuhiro Ito, Nobuhisa Iwata, Junko Kuno, Hiroshi Takano, Osamu Minowa, Kazuo Chihara, Toshimitsu Matsui, T Noda   +8 more
openalex   +1 more source

G proteins of the Gq family couple the H2 histamine receptor to phospholipase C. [PDF]

, 1996
Bernhard Kühn, Andrea Schmid, Christian Harteneck, Thomas Gudermann, G. Schultz   +4 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6

Nature, 2016
A. Küffer, A. Lakkaraju, A. Mogha, Sarah C Petersen, Kristina Airich, C. Doucerain, Rajlakshmi Marpakwar, Pamela Bakirci, Assunta Senatore, Arnaud Monnard, C. Schiavi, M. Nuvolone, Bianka L. Grosshans, S. Hornemann, F. Bassilana, Kelly R. Monk, A. Aguzzi   +16 more
semanticscholar   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Canonical or non-canonical, all aspects of G protein-coupled receptor kinase 2 in heart failure. [PDF]

Acta Physiol (Oxf)
Kaplan A, El-Samadi L, Zahreddine R, Amin G, Booz GW, Zouein FA.   +5 more
europepmc   +1 more source

Structure of a β1-adrenergic G-protein-coupled receptor

Nature, 2008
Tony Warne, M. Serrano-Vega, J. Baker, R. Moukhametzianov, P. Edwards, R. Henderson, A. Leslie, C. Tate, G. Schertler   +8 more
semanticscholar   +1 more source

Primary Alcohols Modulate the Activation of the G Protein-coupled Receptor Rhodopsin by a Lipid-mediated Mechanism [PDF]

, 1996
Drake C. Mitchell, J. Todd R. Lawrence, Burton J. Litman   +2 more
openalex   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source