Results 271 to 280 of about 1,156,973 (433)

Artificial Intelligence: A New Tool for Structure-Based G Protein-Coupled Receptor Drug Discovery. [PDF]

Biomolecules
Chung J, Hahn H, Flores-Espinoza E, Thomsen ARB.   +3 more
europepmc   +1 more source

Evidence for K⁺ channel control in Vicia guard cells coupled by G‐proteins to a 7TMS receptor mimetic [PDF]

, 1995
F. Armstrong, Michael R. Blatt
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

To activate a G protein-coupled receptor permanently with cell surface photodynamic action in the gastrointestinal tract. [PDF]

World J Gastroenterol
Cui ZJ.
europepmc   +1 more source

The Diverse Roles of Arrestin Scaffolds in G Protein–Coupled Receptor Signaling

Pharmacological Reviews, 2017
Y. Peterson, L. Luttrell
semanticscholar   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

G protein-coupled receptor GPR182 negatively regulates sprouting angiogenesis via modulating CXCL12-CXCR4 axis signaling. [PDF]

Angiogenesis
Chen C, Liu W, Yuan F, Wang X, Xu X, Ling CC, Ge X, Shen X, Li B, Shen Y, Liu D.   +10 more
europepmc   +1 more source

A Proposed Structure for Transmembrane Segment 7 of G Protein-Coupled Receptors Incorporating an Asn-Pro/Asp-Pro Motif [PDF]

, 1998
Karel Konvička, Frank Guarnieri, Juan Antonio Ballesteros‐Cánovas, Harel Weinstein   +3 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

The roles of G protein-coupled receptor kinase 2 in renal diseases. [PDF]

J Cell Mol Med
Du J, Wu X, Ni L.
europepmc   +1 more source