Results 71 to 80 of about 496,795 (111)
Some of the next articles are maybe not open access.
G protein—coupled receptor kinases
Cell, 1993G protein‐coupled receptor kinases (GRKs) constitute a family of six mammalian serine/threonine protein kinases that phosphorylate agonist-bound, or activated, G protein‐coupled receptors (GPCRs) as their primary substrates. GRK-mediated receptor phosphorylation rapidly initiates profound impairment of receptor signaling, or desensitization.
openaire +2 more sources
G‐Protein–Coupled Receptor Deorphanizations
2005G protein–coupled receptors (GPCRs) are major regulators of intercellular interactions. They initiate these actions by being activated by a wide variety of natural ligands. Historically, ligands were discovered first, but the advent of molecular biology reversed this trend.
Yumiko, Saito, Olivier, Civelli
openaire +2 more sources
2012
G protein coupled receptors play an important role due to physiological and pathophysiological processes and are responsible for signal transduction in the cell. Furthermore, about 30 % of drugs, present on market, address G protein coupled receptors. First, the families for classification of G protein coupled receptors are presented.
Andrea Strasser, Hans-Joachim Wittmann
openaire +2 more sources
G protein coupled receptors play an important role due to physiological and pathophysiological processes and are responsible for signal transduction in the cell. Furthermore, about 30 % of drugs, present on market, address G protein coupled receptors. First, the families for classification of G protein coupled receptors are presented.
Andrea Strasser, Hans-Joachim Wittmann
openaire +2 more sources
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
G-protein-coupled receptor websites
Trends in Pharmacological Sciences, 2002Brinda K, Rana, Paul A, Insel
openaire +2 more sources
G Protein‐Coupled Receptor Kinases
Journal of Neurochemistry, 1994T, Haga, K, Haga, K, Kameyama
openaire +2 more sources
Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling
Cell, 2021Shuya Kate Huang +2 more
exaly