Results 171 to 180 of about 470,203 (387)

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review

open access: yesNeuropsychiatric Disease and Treatment
Athanasia Giannopoulos,1 Joshna Singh,2 Kristina M Deligiannidis1,3 1Division of Psychiatry Research, Zucker Hillside Hospital, Northwell Health, New York, NY, USA; 2Department of Psychiatry, Jacobs School of Medicine and Biomedical Sciences, University ...
Giannopoulos A   +2 more
doaj  

Predictive value of seizure onset for gross motor dysfunction in individuals with pathogenic GABRB2 and GABRB3 variants

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz   +73 more
wiley   +1 more source

Depressive symptoms as independent correlates of epilepsy‐related cognitive burden

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to assess the relationship between the severity of depression and anxiety symptoms and epilepsy‐related variables and cognitive burden in people with epilepsy (PwE), as assessed using EpiTrack. Methods We prospectively enrolled a cohort of PwE who underwent EpiTrack and evaluation by Generalized Anxiety ...
Biagio Maria Sancetta   +10 more
wiley   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

open access: yesEpilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng   +11 more
wiley   +1 more source

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

open access: yesEpilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh   +10 more
wiley   +1 more source

Effect of acetaminophen use on GABA, NMDA, and synaptic plasticity-related genes in the immature mouse brain: A preliminary study

open access: yesThe EuroBiotech Journal
Background/aim: Acetaminophen is frequently used as an analgesic during pregnancy. The purpose of the present study was to evaluate the effects of acetaminophen administered to pregnant mice on the fetal brain, attention, memory, and learning functions ...
Göl Mehmet Fatih   +8 more
doaj   +1 more source

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