Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar +4 more
wiley +1 more source
Lactic Acid Bacteria-Derived γ-Aminobutyric Acid: From Targeted Screening and Biosynthesis to Functional Food Applications and Health Benefits. [PDF]
Zhang Y +6 more
europepmc +1 more source
Auditory gamma‐band synchronization and attentional performance in juvenile myoclonic epilepsy
Abstract Objective Cognitive difficulties in juvenile myoclonic epilepsy (JME) are part of the clinical phenotype alongside epileptic seizures; however, the underlying neurophysiological mechanisms remain unclear. Auditory steady‐state responses (ASSRs) to repetitive 40‐ and 80‐Hz stimuli are widely used measures of gamma‐band oscillations (GBOs ...
Ryo Mitoma +12 more
wiley +1 more source
Insights Into Aggregation-Delayed Phenotype of Dictyostelium discoideum. [PDF]
Alamer SA.
europepmc +1 more source
Bilateral detection, prediction, and lateralization of seizures using white matter
Abstract Objective To determine how the corpus callosum handles interhemispheric seizure propagation and to assess its potential as a strategic recording locus for state‐dependent biomarkers. Methods Epileptiform activity was induced in vitro and in vivo using 4‐aminopyridine. Propagation dynamics were examined using cross‐correlation analysis.
Nrupen Pakalapati +3 more
wiley +1 more source
Foliar application of gamma aminobutyric acid regulates sulfur metabolism and restores redox balance to improve aluminum tolerance in <i>Camelina sativa</i>. [PDF]
Murtaza G +9 more
europepmc +1 more source
Fermentation enhances nutritional & techno‐functional properties of plant protein. Three distinct stages of fermentation impact on different aspects of plant protein. Fermentation induces flavors modulation through new organic compounds formation. Plant protein fermentation improves their utility in food applications.
Disha +3 more
wiley +1 more source
Effects of exogenous γ-aminobutyric acid concentrations on growth and nutrient uptake in trifoliate orange (<i>Poncirus trifoliata</i>) seedlings under boron-deficient and -sufficient conditions. [PDF]
Jin T, Xu Y, Hu Y, Yao F, Liu G.
europepmc +1 more source
Pulsed light technology uses short high‐intensity broad‐spectrum flashes (200–1100 nm) to inactivate microbes via DNA damage. It preserves food quality, extends shelf life, and works on liquids, meats, and produce, often combined with other hurdles for enhanced efficacy.
Abdul Mueez Ahmad +4 more
wiley +1 more source
The CAGE Framework (Calcium-Gated Excitability): From Single Neurotransmitters to Calcium States in the Tumor Microenvironment. [PDF]
Rudy LM, Godlewski MM.
europepmc +1 more source

