Results 31 to 40 of about 163,092 (297)
Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons
eLife, 2020 In violation of Dale’s principle several neuronal subtypes utilize more than one classical neurotransmitter. Molecular identification of vesicular glutamate transporter three and cholecystokinin expressing cortical interneurons (CCK+VGluT3+INTs) has ...
Kenneth A Pelkey +16 more
doaj +1 more source
Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels
Acta Pharmaceutica, 2018 In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated.
Vega Rasgado Lourdes A. +2 more
doaj +1 more source
Biomolecules, 2019 Screening for various types of lactic acid bacteria (LAB) that form the biological agent γ-amino-butyric acid (GABA) is important to produce different kinds of GABA-containing fermented foods.
Dalin Ly +4 more
doaj +1 more source
Intestinal Microbiota and Sleep Inversion
Педиатрическая фармакология, 2022 Various human lifestyle and environmental factors are known to influence sleep. The number of adults and children suffering from chronic sleep disorders has grown over the past decade.
Anatoly I. Khavkin +2 more
doaj +1 more source
Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
Effect of germination on main physiology and biochemistry metabolism of sorghum seeds
Bioscience Journal, 2016 The main physiology and biochemistry metabolism including amino acids composition and gamma-aminobutyric acid (GABA) content of sorghum during 3-day germination period was investigated. Respiratory rate increased during germination.
Runqiang Yang +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis +5 more
wiley +1 more source
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
Advanced Science, EarlyView.In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao +12 more
wiley +1 more source
Epilepsia idiopática em cães: Novos tratamentos e impactos sobre os animais e tutores
Pubvet, 2022 A convulsão é a manifestação clínica da atividade elétrica anormal do cérebro, é qualquer evento não específico, e epilepsia refere-se a múltiplas convulsões que ocorrem durante um longo período. Conceituar e compreender como a epilepsia influencia o bem-
Franciele Taiza Borges do Nascimento +3 more
doaj +1 more source
Advanced Science, EarlyView.CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi +8 more
wiley +1 more source