Results 31 to 40 of about 245,202 (346)

GABA and mood disorders [PDF]

open access: yesPsychological Medicine, 2003
A γ-aminobutyric acid (GABA)-ergic theory of mood disorders was proposed by Emrich and colleagues (1980) following observations of the efficacy of the GABAergic anticonvulsant, valproate, in the treatment of mania. Since then, increasing biochemical and pharmacological evidence from animal and human studies has supported the hypothesis that mood ...
Taylor, MJ   +3 more
openaire   +6 more sources

Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice

open access: yesJournal of Integrative Neuroscience, 2023
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system.
Qais Jarrar   +8 more
doaj   +1 more source

Characterization of GABA Receptors [PDF]

open access: yesCurrent Protocols in Pharmacology, 1998
AbstractDescribed in this unit are ligand‐binding assays for GABAA, GABAB, and the homomeric ρ GABAA(formerly GABAC) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS.
Kenneth E. McCarson, S.J. Enna
openaire   +2 more sources

Astrocyte-Ablation of Mtnr1b Increases Anxiety-Like Behavior in Adult Male Mice

open access: yesJournal of Integrative Neuroscience, 2023
Background: Astrocytes are essential for synaptic transmission, and their dysfunction can result in neuropsychiatric disorders such as anxiety and depression.
Zijun Meng   +11 more
doaj   +1 more source

Effectiveness of germinated brown rice on metabolic syndrome: A randomized control trial in Vietnam

open access: yesAIMS Public Health, 2020
To treating Metabolic Syndrome (MetS) in the human body by using cooked pre- germinated brown rice (PGBR), a randomized control trial was done in Vietnam. 80 subjects (65.1 ± 3.81 years old) separated into two groups in pairs were assigned a daily intake
Truong Tuyet Mai   +2 more
doaj   +1 more source

Identification of Novel Prognostic Biomarkers That are Associated with Immune Microenvironment Based on GABA-Related Molecular Subtypes in Gastric Cancer

open access: yesPharmacogenomics and Personalized Medicine, 2023
Beibei Wang, Linlin Huang, Shanliang Ye, Zhongwen Zheng, Shanying Liao Department of Gastroenterology and Hepatology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, People’s Republic of ...
Wang B, Huang L, Ye S, Zheng Z, Liao S
doaj  

A genetically encoded fluorescent sensor for in vivo imaging of GABA

open access: yesNature Methods, 2018
Current techniques for monitoring GABA (γ-aminobutyric acid), the primary inhibitory neurotransmitter in vertebrates, cannot follow transients in intact neural circuits.
J. Marvin   +14 more
semanticscholar   +1 more source

Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

open access: yesIndian Journal of Neurosurgery, 2013
Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons ...
Jyotirmoy Banerjee   +2 more
doaj   +1 more source

sleep disorders due to neuroinfections: clinical symptoms, neurochemistry and neurophysiology V.B. Voitenkov1, N.V. Skripchenko1, Y.E. Zueva 2

open access: yesЖурнал инфектологии, 2015
In our review we present data on sleep disturbances in neuroinfections (encephalitis and meningitis), their clinical signs, neurochemistry and neurophysiology.
V. B. Voitenkov   +2 more
doaj   +1 more source

Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons

open access: yeseLife, 2020
In violation of Dale’s principle several neuronal subtypes utilize more than one classical neurotransmitter. Molecular identification of vesicular glutamate transporter three and cholecystokinin expressing cortical interneurons (CCK+VGluT3+INTs) has ...
Kenneth A Pelkey   +16 more
doaj   +1 more source

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