Results 41 to 50 of about 245,202 (346)

VTA GABA Neurons at the Interface of Stress and Reward

Front. Neural Circuits, 2019
The ventral tegmental area (VTA) is best known for its robust dopaminergic projections to forebrain regions and their critical role in regulating reward, motivation, cognition, and aversion.
C. Bouarab, Brittney Thompson, Abigail M. Polter   +2 more
semanticscholar   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

Acta Pharmaceutica, 2018
In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated.
Vega Rasgado Lourdes A., Reyes Guillermo Ceballos, Vega Díaz Fernando   +2 more
doaj   +1 more source

Identification, Classification and Screening for γ-Amino-butyric Acid Production in Lactic Acid Bacteria from Cambodian Fermented Foods

Biomolecules, 2019
Screening for various types of lactic acid bacteria (LAB) that form the biological agent γ-amino-butyric acid (GABA) is important to produce different kinds of GABA-containing fermented foods.
Dalin Ly, Sigrid Mayrhofer, I. B. Agung Yogeswara, Thu-Ha Nguyen, Konrad J. Domig   +4 more
doaj   +1 more source

Exogenous GABA enhances muskmelon tolerance to salinity-alkalinity stress by regulating redox balance and chlorophyll biosynthesis

BMC Plant Biology, 2019
BackgroundSalinity-alkalinity stress is one of the major abiotic stresses affecting plant growth and development. γ-Aminobutyrate (GABA) is a non-protein amino acid that functions in stress tolerance.
Xiaoqing Jin, Tao Liu, Jiaojiao Xu, Zixing Gao, Xiaohui Hu   +4 more
semanticscholar   +1 more source

Toward Advancement of Fabrication Techniques of Neuromorphic Computing Devices Based on 2D Materials

Advanced Materials Technologies, EarlyView.
This review highlights emerging fabrication techniques of 2D material‐based neuromorphic devices, emphasizing proximity vapor transfer for bioinspired optoelectronic applications. Abstract The growing necessity for power‐efficient and cognitive computation mechanisms has driven progress in neuromorphic computing which seeks to imitate the synaptic ...
Shubham Umeshkumar Gupta, Malkeshkumar Patel, Naveen Kumar, László Pohl, Min‐Joon Park, Sung‐Min Youn, Chaewhan Jeong, Joondong Kim   +7 more
wiley   +1 more source

Effect of germination on main physiology and biochemistry metabolism of sorghum seeds

Bioscience Journal, 2016
The main physiology and biochemistry metabolism including amino acids composition and gamma-aminobutyric acid (GABA) content of sorghum during 3-day germination period was investigated. Respiratory rate increased during germination.
Runqiang Yang, Peng Wang, Maha F. Elbaloula, Zhenxin Gu   +3 more
doaj   +1 more source

Chemoselective Synthesis of α‐Chloro and α,α‐Dichloro Acetamidines via the Carbenoids Addition to Inherently Low Electrophilic Carbodiimides

Advanced Synthesis &Catalysis, EarlyView.
Carbodiimides act as competent electrophilic synthons for the chemoselective addition of lithium mono‐ and di‐halocarbenoids. The transformation is provided through a single synthetic operation—hitherto elusive—halogenated acetamidines. Interestingly, the constitutively tamed electrophilicity of the starting materials is effectively counterbalanced by ...
Davide Castiglione, Margherita Miele, Alberto Nardi, Laura Castoldi, Vittorio Pace   +4 more
wiley   +1 more source

Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models

Translational Psychiatry, 2018
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high human and economic burden. The pathophysiology of ASD is largely unclear, thus hampering development of pharmacological treatments for the core symptoms of the disorder.
J. Horder, M. Petrinovic, M. Mendez, A. Bruns, T. Takumi, W. Spooren, G. Barker, B. Künnecke, D. Murphy   +8 more
semanticscholar   +1 more source

Three‐Component Synthesis of γ‐Amino Esters with α‐Quaternary Carbon Centers via NHC/Photoredox Dual Catalysis

Advanced Synthesis &Catalysis, EarlyView.
γ‐Amino acid derivatives with an α‐quaternary center are prevalent in medicinally important compounds. A dual N‐heterocyclic carbene/photocatalytic pathway is developed for the three‐component synthesis of α, α ‐disubstituted γ‐amino esters. This methodology allows for the rapid synthesis of diverse libraries of γ‐amino esters in good yields.
Adam X. Wayment, Karl A. Scheidt
wiley   +1 more source