Glutamate Decarboxylase from Lactic Acid Bacteria—A Key Enzyme in GABA Synthesis
Glutamate decarboxylase (l-glutamate-1-carboxylase, GAD; EC 4.1.1.15) is a pyridoxal-5’-phosphate-dependent enzyme that catalyzes the irreversible α-decarboxylation of l-glutamic acid to γ-aminobutyric acid (GABA) and CO2.
Ida Bagus Agung Yogeswara +2 more
semanticscholar +1 more source
Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol. [PDF]
Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery.
Durazzo, Timothy C +3 more
core +2 more sources
Background Salt stress is a serious abiotic stress that caused crop growth inhibition and yield decline. Previous studies have reported on the the synthesis of gamma-aminobutyric acid (GABA) and its relationship with plant resistance under various ...
Xiaolei Wu +6 more
semanticscholar +1 more source
Investigation on Hypothalamic GABAergic system difference of local and Leghorn hens based on RNA-Seq dataset [PDF]
Objective: g-Aminobutyric acid (GABA) is a non-protein amino acid synthesized by decarboxylation of glutamate by the enzyme glutamic acid decarboxylase. The central nervous system (CNS) contains uniquely high concentrations of GABA, and GABA serves as a ...
Yadollah Badakhshan +2 more
doaj +1 more source
Structure of a human synaptic GABA-A receptor
Fast inhibitory neurotransmission in the brain is principally mediated by the neurotransmitter GABA (γ-aminobutyric acid) and its synaptic target, the type A GABA receptor (GABAA receptor).
Shaotong Zhu +5 more
semanticscholar +1 more source
In our review we present data on sleep disturbances in neuroinfections (encephalitis and meningitis), their clinical signs, neurochemistry and neurophysiology.
V. B. Voitenkov +2 more
doaj +1 more source
Psychotic Episodes After Vigabatrine Treatment: A Case Report
Vigabatrin is an antiepileptic that functions by increasing ɣ-aminobutyric acid (GABA) levels in the brain. Like other antiepileptics, it also causes neuropsychiatric side effects. Among these side effects, psychosis draws particular attention. Drug-
Erdem Uysal +2 more
doaj +1 more source
Investigation of the Effect of Anakinra on Pentylenetetrazole-Induced Epileptic Seizures in Mice
Purpose: Disruption of the balance between gamma aminobutyric acid (GABA) and glutamate in the brain is one of the important factors contributing to seizure formation and epileptogenesis.
Ahmet Kemal FİLİZ +1 more
doaj +1 more source
An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]
There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C. +5 more
core +1 more source
Chasing after minerality, relationship to yeasts nutritional stress and succinic acid production
Minerality is certainly one of the most mysterious and most valuable tones of wine taste and it is very often associated with the concept of terroir. The isotachophoresis was used for determination of cations - minerals in two wines from vineyards with ...
Mojmír Baroň, Jaromír Fiala
doaj +1 more source

