Results 41 to 50 of about 333,224 (356)

In Vivo GABA Detection by Single Pulse Editing with One Shot [PDF]

open access: yesarXiv, 2023
Over the past two decades, magnetic resonance spectroscopy with two-shot difference editing has been widely employed to characterize altered levels of GABA, the primary inhibitory neurotransmitter in the brain, in various neuropsychiatric disorders. This conventional technique detects the GABA H4 resonance, making it unsuitable for investigating GABA ...
arxiv  

Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]

open access: yes, 2012
Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S   +8 more
core   +2 more sources

The role of chitosan priming in induction of GABA shunt pathway during wheat seed germination under salt stress

open access: yesBiologia Plantarum, 2023
Soil salinity leads to a reduction in plant growth, germination, relative water content, and production of wheat plants worldwide. Chitosan showed a positive effect on plant growth and development and improved plant stress tolerance.
N.A. Al-Quraan   +2 more
doaj   +1 more source

Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model [PDF]

open access: yes, 2016
peer-reviewedThe aim of this study was to investigate if dietary administration of γ-aminobutyric acid (GABA)-producing Lactobacillus brevis DPC 6108 and pure GABA exert protective effects against the development of diabetes in streptozotocin (STZ ...
Cotter, Paul D.   +9 more
core   +1 more source

Psychiatric morbidity among men using anabolic steroids

open access: yesDepression and Anxiety, Volume 39, Issue 12, Page 805-812, December 2022., 2022
Abstract Objective The purpose of this study was to investigate the psychiatric morbidity among men with abuse of anabolic steroids. Methods The design is a retrospectively matched cohort study. Five hundred and fourty‐five males, who tested positive for anabolic steroids in Danish fitness centers during the period January 3, 2006 to March 1, 2018 ...
Josefine Windfeld‐Mathiasen   +5 more
wiley   +1 more source

Mesencephalic GABA neuronal development: no more on the other side of oblivion

open access: yesBiomolecular Concepts, 2014
Midbrain GABA neurons, endowed with multiple morphological, physiological and molecular characteristics as well as projection patterns are key players interacting with diverse regions of the brain and capable of modulating several aspects of behavior ...
Li Suyan, Joshee Sampada, Vasudevan Anju
doaj   +1 more source

Characterization of GABA Receptors [PDF]

open access: yesCurrent Protocols in Pharmacology, 1998
AbstractDescribed in this unit are ligand‐binding assays for GABAA, GABAB, and the homomeric ρ GABAA (formerly GABAC) receptor recognition sites in brain tissue. Although GABA binding sites are present in peripheral organs, most research is directed toward examining these receptors in the CNS.
Kenneth E. McCarson, S.J. Enna
openaire   +2 more sources

Adansonia digitata L. Stem Bark Attenuates Epileptic Seizure, Depression, and Neurodegeneration by Mediating GABA and Glutamate in Pentylenetetrazol-Kindled Rats

open access: yesJournal of Pharmacopuncture, 2023
Objectives: Epilepsy is a neurological condition characterized by repeated seizures attributable to synchronous neuronal activity in the brain. The study evaluated the effect of acetone extract of Adansonia digitata stem bark (ASBE) on seizure score ...
Adamu Muhammad   +4 more
doaj   +1 more source

Effects of Short Time-High Voltage Electric Field Treatment on the Accumulation of γ-Aminobutyric Acid in Germinated Buckwheat

open access: yesLiang you shipin ke-ji, 2022
The short-time high-voltage electric field treatment was used to increase the GABA content of buckwheat after germination, and the activities of GABA shunt enzymes were measured.
YANG Shang-ru   +3 more
doaj   +1 more source

Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]

open access: yes, 2015
Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO   +3 more
core   +1 more source

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