Results 51 to 60 of about 245,202 (346)
Epilepsia idiopática em cães: Novos tratamentos e impactos sobre os animais e tutores
Pubvet, 2022 A convulsão é a manifestação clínica da atividade elétrica anormal do cérebro, é qualquer evento não específico, e epilepsia refere-se a múltiplas convulsões que ocorrem durante um longo período. Conceituar e compreender como a epilepsia influencia o bem-
Franciele Taiza Borges do Nascimento +3 more
doaj +1 more source
Intestinal Microbiota and Sleep Inversion
Педиатрическая фармакология, 2022 Various human lifestyle and environmental factors are known to influence sleep. The number of adults and children suffering from chronic sleep disorders has grown over the past decade.
Anatoly I. Khavkin +2 more
doaj +1 more source
Cogent Food & Agriculture, 2019 Υ-aminobutyric acid (GABA) is a non-protein amino acid in a wide range of organisms. In plants, GABA is proposed to take multiple functions under non-stressed and stressed conditions.
Roberto Ramos-Ruiz +2 more
semanticscholar +1 more source
Advanced Synthesis &Catalysis, EarlyView.GA: Strained small motifs and SuFEx hubs are of increasing importance in drug discovery to enable efficient late‐stage functionalization. Here, the synthesis of bench‐stable azabicyclo[1.1.0]butyl‐substituted sulfonimidoyl fluoride as an electrophilic hub with dual activation mode is reported.
Defne Serbetci +5 more
wiley +1 more source
Biomolecules, 2019 N-methyl-d-aspartate/glutamate receptor (NMDAR) is one of the major voltage-sensitive ligand-gated cation channel. Several noncompetitive NMDAR antagonists contribute to pathophysiology of schizophrenia and mood disorders; however, the effects of ...
Motohiro Okada +3 more
doaj +1 more source
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep
Pharmaceutical Biology, 2019 Context: γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter and it is well established that activation of GABAA receptors favours sleep.
Suhyeon Kim +4 more
semanticscholar +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Frontiers in Plant Science, 2018 Plant responses to salinity are complex, especially when combined with other stresses, and involve many changes in gene expression and metabolic fluxes. Until now, plant stress studies have been mainly dealt only with a single stress approach.
P. Carillo
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song +24 more
wiley +1 more source
Effect of Rich GABA of Germinated Adzuki Bean on Intestinal Microflora in T2DM Mice
Shipin gongye ke-jiIn order to study the effects of GABA-rich germinated adzuki bean on blood glucose level and intestinal flora in T2DM mice. C57BL/6J mice were used as subjects to construct T2DM model by high fat diet+STZ injection.
Xiujie JIANG +6 more
doaj +1 more source