Results 91 to 100 of about 47,360 (258)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Alterations in gamma-aminobutyric acid and glutamate neurotransmission linked to intermittent theta-burst stimulation in depression: a sham-controlled study

open access: yesTranslational Psychiatry
Gamma-aminobutyric acid (GABA) and glutamate are implicated in the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS), though findings from magnetic resonance spectroscopy (MRS) are inconsistent.
Linda Steinholtz   +5 more
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet   +5 more
wiley   +1 more source

Junctional conductance of retinal AII amacrine cell electrical synapses is decreased by NMDA receptors

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend AII amacrine cells are an important class of interneuron in the vertebrate retina. In addition to traditional chemical synapses these cells communicate with other neurons and with each other via electrical synapses. (A) Electrical synapse strength between AII amacrine cells was measured using dual whole‐cell patch‐clamp ...
Chloe Cable   +2 more
wiley   +1 more source

GABAA Receptor [PDF]

open access: yesScience-Business eXchange, 2010
Husseini K. Manji   +58 more
openaire   +2 more sources

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