WWC2 modulates GABA<sub>A</sub>-receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins. [PDF]
Dunham TL+4 more
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A Role for GABAA Receptor β3 Subunits in Mediating Harmaline Tremor Suppression by Alcohol: Implications for Essential Tremor Therapy. [PDF]
Handforth A+3 more
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Haploinsufficiency of GABAA Receptor-Associated Clptm1 Enhances Phasic and Tonic Inhibitory Neurotransmission, Suppresses Excitatory Synaptic Plasticity, and Impairs Memory. [PDF]
Ge Y, Craig AM.
europepmc +1 more source
Modulators of GABAA receptor-mediated inhibition in the treatment of neuropsychiatric disorders: past, present, and future. [PDF]
Thompson SM.
europepmc +1 more source
GABAA receptor subunit M2-M3 linkers have asymmetric roles in pore gating and diazepam modulation. [PDF]
Nors JW, Endres Z, Goldschen-Ohm MP.
europepmc +1 more source
β-carbolines that enhance GABAA receptor response expressed in oligodendrocytes promote remyelination in an in vivo rat model of focal demyelination. [PDF]
Cisneros-Mejorado AJ+3 more
europepmc +1 more source
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Pharmacological modulation of GABAA receptors
Current Opinion in Pharmacology, 2021Ligand-gated ion channels are integral membrane proteins that activate through a change in conformation upon transmitter binding and were identified as key players of brain function. GABAA receptors are major inhibitory ligand-gated ion channels of this protein family.
Frédéric Knoflach, Daniel Bertrand
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