Results 151 to 160 of about 39,325 (214)

A Role for δ Subunit-Containing GABA_A Receptors on Parvalbumin-Positive Neurons in Maintaining Electrocortical Signatures of Sleep States. [PDF]

J Neurosci
Lambert PM, Salvatore SV, Lu X, Shu HJ, Benz A, Rensing N, Yuede CM, Wong M, Zorumski CF, Mennerick S.   +9 more
europepmc   +1 more source

Multistage Molecular Simulations, Design, Synthesis, and Anticonvulsant Evaluation of 2-(Isoindolin-2-yl) Esters of Aromatic Amino Acids Targeting GABA_A Receptors via π-π Stacking. [PDF]

Int J Mol Sci
González-Periañez S, Hernández-Rosas F, López-Rosas CA, Ramos-Morales FR, Zurutuza-Lorméndez JI, García-Rodríguez RV, Olivares-Romero JL, Ramos-Hernández RR, Bravo-Espinoza I, Vidal-Limon A, Pawar TJ.   +10 more
europepmc   +1 more source

Phenols and GABA_A receptors: from structure and molecular mechanisms action to neuropsychiatric sequelae. [PDF]

Front Pharmacol
Menzikov SA, Zaichenko DM, Moskovtsev AA, Morozov SG, Kubatiev AA.   +4 more
europepmc   +1 more source

Neurosteroid Modulation of Synaptic and Extrasynaptic GABA_A Receptors of the Mouse Nucleus Accumbens. [PDF]

Biomolecules
Mitchell SJ, Phillips GD, Tench B, Li Y, Belelli D, Martin SJ, Swinny JD, Kelly L, Atack JR, Paradowski M, Lambert JJ.   +10 more
europepmc   +1 more source

Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABA_A receptors. [PDF]

RSC Adv
Qian M, Xu Y, Shu HJ, Chen ZW, Wang L, Zorumski CF, Evers AS, Mennerick S, Covey DF.   +8 more
europepmc   +1 more source

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An update on GABAA receptors

Brain Research Reviews, 1999
Recent advances in molecular biology and complementary information derived from neuropharmacology, biochemistry and behavior have dramatically increased our understanding of various aspects of GABAA receptors. These studies have revealed that the GABAA receptor is derived from various subunits such as alpha1-alpha6, beta1-beta3, gamma1-gamma3, delta ...
A K, Mehta, M K, Ticku
openaire   +2 more sources

Pharmacological modulation of GABAA receptors

Current Opinion in Pharmacology, 2021
Ligand-gated ion channels are integral membrane proteins that activate through a change in conformation upon transmitter binding and were identified as key players of brain function. GABAA receptors are major inhibitory ligand-gated ion channels of this protein family.
Frédéric, Knoflach, Daniel, Bertrand
openaire   +2 more sources

Molecular Biology of the GABAA Receptor

1988
The GABAA receptorreceptor is the major molecular site of the ubiquitous inhibitory acEivities of the brain, being present on the great majority of mammalian brain neurones (1). Electrophysiological studies and, especially, recent patch-clamp studies on cultured neurones (2,3) have established that at these sites GABA opens a chloride channel which is ...
Barnard, E., Darlison, M., Fujita, N., Glencorse, T., Levitan, E., Reale, V., Schofield, P., Seeburg, P., Squire, M., Stephenson, A.   +9 more
openaire   +3 more sources