Results 171 to 180 of about 39,325 (214)
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Multiplicity of GABAA-benzodiazepine receptors
Trends in Pharmacological Sciences, 1989Binding studies suggest the presence of at least two pharmacologically distinct 'central' benzodiazepine receptors in the brain. Since central benzodiazepine receptors are allosteric modulatory sites on GABAA receptors, this evidence indirectly points to the existence of at least two GABAA receptors.
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Hijacking of GABAA Receptors by Mutant Glycine Receptors
Trends in Molecular Medicine, 2019Startle disease results from mutations in genes encoding inhibitory GlyR α1 and β subunits or the presynaptic glycine transporter GlyT2. However, the most effective therapies are benzodiazepines that potentiate inhibitory GABAAR function. A recent publication by Zou et al.
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Proteostasis Regulators Restore Function of Epilepsy-Associated GABAA Receptors
Cell Chemical Biology, 2021Xiao-Jing Di +2 more
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Probing the GABAA receptor with antibodies
Biochemical Society Transactions, 1991A J, Turner, K B, Widdows, E F, Kirkness
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GABAA receptors are differentially sensitive to zinc: dependence on subunit composition
British Journal of Pharmacology, 1991T G Smart, S J Moss, Richard L Huganir
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