Results 161 to 170 of about 75,987 (290)

Ninjurin1 in cardiovascular and vascular biology: From molecular mechanisms to therapeutic opportunities

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley   +1 more source

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman, An‐Ping Ye, Ya‐Xian Zhang, Ming‐Yu Chen, Fang Huang, Rong Liu, Ying‐Yan Fang, Xiaochuan Wang   +7 more
wiley   +1 more source

Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP [PDF]

, 2014
Enrica Maria Petrini, Tiziana Ravasenga, Torben J. Hausrat, Giuliano Iurilli, Umberto Olcese, Victor Racine, Jean‐Baptiste Sibarita, Tija C. Jacob, Stephen J. Moss, Fabio Benfenati, Paolo Medini, Matthias Kneussel, Andrea Barberis   +12 more
openalex   +1 more source

Zuranolone, a positive allosteric modulator of the GABAA receptor and a neuroactive steroid: hypothesized mechanism of action in depression

, 2023
Jason Payne, Jodi L. Pawluski, Astrid Althaus, Shirley J. Gee, Tomás Ripoll‐Vera, Nicholas D’Alberto, Simon Kyaga, M. Kotecha, Mark H. Pollack, Roger S. McIntyre, Stephen M. Stahl   +10 more
openalex   +1 more source

Pharmacologic Treatment of Kleine–Levin Syndrome: A Case Report and Comprehensive Review of Therapeutic Options

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
A 12‐year‐old girl with Klein‐Levin syndrome showed central hypopneas and REM sleep without atonia on 24‐h polysomnography, which normalized after clarithromycin treatment alongside clinical remission. ABSTRACT Kleine–Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents.
Sarisa Thawongit, Vorasith Siripornpanich, Lunliya Thampratankul   +2 more
wiley   +1 more source

Electroacupuncture Suppresses CCI-Induced Neuropathic Pain through GABAA Receptors. [PDF]

Evid Based Complement Alternat Med, 2022
Li S, Jiang X, Wu Q, Jin Y, He R, Hu J, Zheng Y.   +6 more
europepmc   +1 more source

GABAA receptor regulation after experimental traumatic brain injuries

, 2014
Raible, Daniel James
openalex   +1 more source

A neuroactive steroid with a therapeutically interesting constellation of actions at GABAA and NMDA receptors

, 2020
Luke H. Ziolkowski, Isaac Mordukhovich, Daniel M. Chen, Mariangela Chisari, Hong-Jin Shu, Peter Lambert, Mingxing Qian, Charles F. Zorumski, Douglas F. Covey, Steven Mennerick   +9 more
openalex   +2 more sources

GABRB3 Mutation, G32R, Associated with Childhood Absence Epilepsy Alters α1β3γ2L γ-Aminobutyric Acid Type A (GABAA) Receptor Expression and Channel Gating [PDF]

, 2012
Katharine N. Gurba, Ciria C. Hernández, Ningning Hu, Robert L. Macdonald   +3 more
openalex   +1 more source

Evaluating and Determining the Effects of Psychotropic Drugs on Motor Vehicle Driving Performance: Key Considerations of the Japanese Guideline and Criteria for Clinical Implementation of Evidence

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
The Japanese guideline and criteria for evaluating and determining the effects of psychotropic drugs on motor vehicle driving performance enable the clinical implementation of evidence by assessing “persistence of clinically meaningful impairment”. ABSTRACT The cross‐national differences in automobile driving precautions stated in psychotropic drug ...
Tetsuo Nakabayashi, Kunihiro Iwamoto, Akiko Yamaguchi, Yuki Konishi, Momoe Saji, Reiji Yoshimura, Kousuke Kanemoto, Hirofumi Aoki, Masahiko Ando, Norio Ozaki   +9 more
wiley   +1 more source