Results 171 to 180 of about 75,987 (290)

Analgesic Effect of 17β-Estradiol on Nucleus Paragigantocellularis Lateralis of Male Rats Mediated Via GABAA Receptors

Basic and Clinical Neuroscience, 2017
Introduction: Beside its autonomic functions, the nucleus paragigantocellularis lateralis (LPGi) is involved in the descending pain modulation. 17β-Estradiol is a neuroactive steroid found in several brain areas such as LPGi.
Roghaieh Khakpay, Maryam Azaddar, Fatemeh Khakpay, Homeira Hatami Nemati   +3 more
doaj  

The Effects of Acute and Chronic Ethanol Exposure on Presynaptic and Postsynaptic GABAA Receptor Function in Cultured Cortical and Hippocampal Neurons

, 2020
Rebekah L. Fleming, Paul B. Manis, A. Leslie Morrow   +2 more
openalex   +1 more source

Chronic administration of aripiprazole activates GSK3β-dependent signalling pathways and up-regulates GABAA receptor expression and CREB1 activity in rats [PDF]

, 2016
Bo Pan, Xu‐Feng Huang, Chao Deng
openalex   +1 more source

Population Pharmacokinetic–Pharmacodynamic Analysis of Zolpidem in Healthy Volunteers: Covariate Contributions to Variability in CNS Responses

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Population pharmacokinetic–pharmacodynamic (PK–PD) modeling was used to explore covariate effects on zolpidem PKs and PDs in 30 healthy Korean volunteers (15 males, 15 females) who received a single 10 mg dose. The dataset included 325 PK observations and 388 observations each for the digit symbol substitution test (DSST), choice reaction time
Hyun Chul Kim, Jung Sunwoo, Seonghae Yoon, In‐Jin Jang, Jae‐Yong Chung   +4 more
wiley   +1 more source

Molecular assemblies and pharmacology of cerebellar GABA_A receptors. [PDF]

Proc Natl Acad Sci U S A
Sun C, Jahncke JN, Wright KM, Gouaux E.
europepmc   +1 more source

Electrophysiological sexual dimorphism as an early risk marker of alcohol use in adolescence: A longitudinal neuroimaging study

Addiction, Volume 121, Issue 3, Page 606-616, March 2026.
Abstract Aims To identify the brain activity profiles associated with alcohol consumption and to address its causes. Furthermore, we sought to examine the relationship between these electrophysiological markers and the excitation–inhibition balance, as well as to explore the potential moderating role of sex in these associations.
Alberto del Cerro‐León, Marcos Uceta, Danylyna Shpakivska‐Bilan, Isabel Suárez‐Méndez, Héctor Peribáñez‐Baz, Pablo Cuesta, Ricardo Bruña, Luis M. García‐Moreno, Fernando Maestú, Luis Fernando Antón‐Toro   +9 more
wiley   +1 more source

Recurrent neonatal seizures increase tonic inhibition and respond to enhancers of δ-containing GABAA receptors. [PDF]

JCI Insight
Liddiard GT, Buchanan GF, Schultz ML, Glykys J.   +3 more
europepmc   +1 more source

Structural insights into opposing actions of neurosteroids on GABA_A receptors. [PDF]

Nat Commun, 2023
Legesse DH, Fan C, Teng J, Zhuang Y, Howard RJ, Noviello CM, Lindahl E, Hibbs RE.   +7 more
europepmc   +1 more source

GABAA receptors implicated in REM sleep control express a benzodiazepine binding site

, 2013
Tin Nguyen, Chang‐Lin Liang, Gerald A. Marks   +2 more
openalex   +2 more sources

Prefrontal Cortex Dysfunction as a Precipitating Factor for Schizophrenia and Depression

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Stress during adolescence or adulthood affects the ability of the prefrontal cortex (PFC) to adaptively regulate stress. Maladaptive adult stress leads to PFC hypofunction and a hypodopaminergic state in the medial, affect‐related ventral tegmental area (VTA), resulting in amotivation.
Daniela L. Uliana, Anthony A. Grace
wiley   +1 more source