Results 41 to 50 of about 759,534 (341)

Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells

Aging and Disease, 2017
GABAergic neuronal cell grafting has promise for treating a multitude of neurological disorders including epilepsy, age-related memory dysfunction, Alzheimer’s disease and schizophrenia.
Qianfa Long, Q. Luo, Kai Wang, A. Bates, A. Shetty   +4 more
semanticscholar   +1 more source

A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila

Front. Neural Circuits, 2014
Inhibition has a central role in defining the selectivity of the responses of higher order neurons to sensory stimuli. However, the circuit mechanisms of regulation of these responses by inhibitory neurons are still unclear.
L. Masuda-Nakagawa, Kei Ito, T. Awasaki, C. O’Kane   +3 more
semanticscholar   +1 more source

Birthdate study of GABAergic neurons in the lumbar spinal cord of the glutamic acid decarboxylase 67-green fluorescent protein knock-in mouse

Frontiers in Neuroanatomy, 2013
Despite the abundance of studies on γ-aminobutyric acid (GABA) ergic neuron distribution in the mouse developing spinal cord, no investigation has been devoted so far to their birthdates.
Jing eHuang, Jing eChen, Wen eWang, Guo-Hong eCai, Yan-Yan eWei, Shengxi eWu   +5 more
doaj   +1 more source

Hypothalamic GABAergic neurocircuitry in the regulation of energy homeostasis and sleep/wake control

Medical Review, 2022
Gamma-aminobutyric acid (GABAergic) neuron, as one of important cell types in synaptic transmission, has been widely involved in central nervous system (CNS) regulation of organismal physiologies including cognition, emotion, arousal and reward. However,
Jiang Hong
doaj   +1 more source

A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex

Cell Reports, 2018
Summary: More specific and broadly applicable viral gene-targeting tools for labeling neuron subtypes are needed to advance neuroscience research, especially in rodent transgenic disease models and genetically intractable species.
Marianna K. Keaveney, Hua-an Tseng, Tina L. Ta, Howard J. Gritton, Heng-Ye Man, Xue Han   +5 more
doaj   +1 more source

Innervation by a GABAergic Neuron Depresses Spontaneous Release in Glutamatergic Neurons and Unveils the Clamping Phenotype of Synaptotagmin-1

Journal of Neuroscience, 2014
The role of spontaneously occurring release events in glutamatergic and GABAergic neurons and their regulation is intensely debated. To study the interdependence of glutamatergic and GABAergic spontaneous release, we compared reciprocally connected ...
Keimpe D. B. Wierda, J. B. Sørensen
semanticscholar   +1 more source

GABAergic neurons are susceptible to BAX-dependent apoptosis following isoflurane exposure in the neonatal period.

PLoS ONE, 2021
Exposure to volatile anesthetics during the neonatal period results in acute neuron death. Prior work suggests that apoptosis is the dominant mechanism mediating neuron death.
Andrew M Slupe, Laura Villasana, Kevin M Wright   +2 more
doaj   +1 more source

Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice

Neurobiology of Disease, 2021
In view of the negative regulatory effect of leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO-1) on neurons, an antibody against LINGO-1 (anti-LINGO-1 antibody) was herein administered to 10-month ...
Qi He, Lin Jiang, Yi Zhang, Hao Yang, Chun-Ni Zhou, Yu-Han Xie, Yan-Min Luo, Shan-Shan Zhang, Lin Zhu, Yi-Jing Guo, Yu-Hui Deng, Xin Liang, Qian Xiao, Lei Zhang, Jing Tang, Du-Juan Huang, Yu-Ning Zhou, Xiao-Yun Dou, Feng-Lei Chao, Yong Tang   +19 more
doaj   +1 more source

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

Science, 2023
Human cortex transcriptomic studies have revealed a hierarchical organization of γ-aminobutyric acid–producing (GABAergic) neurons from subclasses to a high diversity of more granular types.
Brian R. Lee, R. Dalley, Jeremy A. Miller, Thomas Chartrand, Jennie L. Close, Rusty Mann, A. Mukora, Lindsay Ng, Lauren Alfiler, Katherine Baker, Darren Bertagnolli, Krissy Brouner, Tamara Casper, Eva Csajbok, Nicholas Donadio, Stan L. W. Driessens, Tom Egdorf, Rachel Enstrom, A. Galakhova, A. Gary, Emily C. Gelfand, Jeff Goldy, Kristen Hadley, Tim S. Heistek, Dijon Hill, W. Hou, Nelson J. Johansen, Nikolas L. Jorstad, Lisa Kim, Á. Kocsis, Lauren Kruse, Michael Kunst, Gabriela Leon, Brian Long, M. Mallory, Michelle Maxwell, M. McGraw, Delissa A. McMillen, E. Melief, G. Molnár, M. Mortrud, Dakota Newman, J. Nyhus, Ximena Opitz-Araya, A. Ozsvár, Trangthanh Pham, A. Pom, L. Potekhina, R. Rajanbabu, Augustin Ruiz, S. Sunkin, Ildikó Szöts, Naz Taskin, B. Thyagarajan, Michael Tieu, Jessica Trinh, Sara Vargas, D. Vumbaco, Femke Waleboer, Sarah Walling-Bell, Natalie Weed, G. Williams, Julia Wilson, Shenqin Yao, Thomas Zhou, Pál Barzó, Trygve E Bakken, Charles Cobbs, N. Dee, Richard G. Ellenbogen, Luke Esposito, Manuel Ferreira, N. Gouwens, Benjamin L. Grannan, R. Gwinn, Jason Hauptman, R. Hodge, T. Jarsky, C. Keene, A. Ko, A. Korshoej, Boaz P. Levi, K. Meier, J. Ojemann, Anoop P. Patel, Jacob Ruzevick, D. Silbergeld, Kimberly A. Smith, J. C. Sørensen, Jack Waters, Hongkui Zeng, J. Berg, M. Capogna, N. Goriounova, B. Kalmbach, C. D. de Kock, H. Mansvelder, S. Sorensen, G. Tamás, E. Lein, J. Ting   +100 more
semanticscholar   +1 more source

Neuronal–Glial Glucose Oxidation and Glutamatergic–GABAergic Function [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2006
Prior 13C magnetic resonance spectroscopy (MRS) experiments, which simultaneously measured in vivo rates of total glutamate-glutamine cycling (Vcyc(tot)) and neuronal glucose oxidation ( CMRglc(ox), N), revealed a linear relationship between these fluxes above isoelectricity, with a slope of ~1.
Hyder, Fahmeed, Patel, Anant B, Gjedde, Albert, Rothman, Douglas L, Behar, Kevin L, Shulman, Robert G   +5 more
openaire   +4 more sources