Results 161 to 170 of about 6,345 (201)

Are gabapentinoids addictive?

Academic Journal of Neurology and Neurosurgery
Gabapentinoids are highly effective drugs used in the treatment of epilepsy, anxiety disorders, and particularly neuropathic pain. In recent years, their use has become a cause for concern as reports on their misuse have increased. Studies have been conducted to identify the patient groups that are prone to the drug’s misuse.
Ceyda Tanoğlu, Ruhsen Öcal
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[Gabapentinoids : misuses and addictions].

Revue medicale suisse, 2021
Cases of addictions and misuses on gabapentinoids are increasingly reported. But the underlying pharmacological mechanism is not completely understood. Here is an uptodate of the current knowledges on this dependence and its management.
Carole, Grandjean, Séverine, Crettol Wavre, Yasser, Khazaal, Javier, Sanchis Zozaya, Nicolas, Ansermot, Frederik, Vandenberghe, Guibet, Sibailly, Chin-Bin, Eap   +7 more
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[On the risk of dependence on gabapentinoids].

Fortschritte der Neurologie-Psychiatrie, 2019
In the last ten years, the prescriptions of the gabapentinoids gabapentin and pregabalin increased largely also in Germany. Since several national and international pharmacovigilance-databases have warned for abuse liabilities and overdose fatalities in association with both gabapentinoids, which moreover, became to be sold on internet and black ...
Udo, Bonnet, Norbert, Scherbaum
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The Anti-Allodynic Gabapentinoids

The Neuroscientist, 2016
The gabapentinoids (pregabalin and gabapentin) are first line treatments for neuropathic pain. They exert their actions by binding to the α2δ accessory subunits of voltage-gated Ca 2+ channels.
Sascha R A, Alles, Peter A, Smith
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Gabapentinoids for RLS

Abstract There are three gabapentinoids on the market: gabapentin, gabapentin enacarbil, and pregabalin. These drugs are considered first-line therapy for RLS. Gabapentin enacarbil and pregabalin tend to be absorbed better and more reliably effective than gabapentin due to variability in how gabapentin is absorbed in the intestines. Side
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Perioperative Use of Gabapentinoids: Reply

Anesthesiology, 2021
Michael, Verret, Ryan, Zarychanski, François, Lauzier, Alexis F, Turgeon   +3 more
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Gabapentinoids

2018
Sergio Canavero, Vincenzo Bonicalzi
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Chronic Gabapentinoid Use and Lumbar Fusion Outcomes

Spine
Study Design. Retrospective comparative cohort study. Objectives. To examine the effects of chronic use of gabapentinoids (GPs) (alone or with opioids) on the outcomes of lumbar fusions. Summary of Background Data.
Riza M. Cetik, Steven D. Glassman, Colleen Mahoney, Jeffrey L. Gum, Charles H. Crawford, Roger K. Owens, John R. Dimar, Benjamin Kostic, Leah Y. Carreon   +8 more
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Association Between Gabapentinoids and Postoperative Pulmonary Complications in Patients Undergoing Thoracic Surgery

Journal of Cardiothoracic and Vascular Anesthesia, 2022
Karthik Raghunathan
exaly  

Concerns About Gabapentinoids in Psychiatric Practice

Journal of Psychosocial Nursing and Mental Health Services
Similar to benzodiazepines, gabapentinoids are used to reduce central nervous system hyperexcitability. Unlike benzodiazepines, gabapentinoids are not approved by the U.S. Food and Drug Administration for the treatment of psychiatric disorders, even in disorders characterized by excitatory-inhibitory imbalances in neuronal circuits. The current article
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