Results 41 to 50 of about 883 (159)

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Oral administration of pyrophosphate inhibits connective tissue calcification

EMBO Molecular Medicine, 2017
Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in ABCC6 and ENPP1, respectively, present with extensive tissue calcification due to reduced ...
Dóra Dedinszki, Flóra Szeri, Eszter Kozák, Viola Pomozi, Natália Tőkési, Tamás Róbert Mezei, Kinga Merczel, Emmanuel Letavernier, Ellie Tang, Olivier Le Saux, Tamás Arányi, Koen van de Wetering, András Váradi   +12 more
doaj   +1 more source

Case Report: A Novel Genetic Mutation Causes Idiopathic Infantile Arterial Calcification in Preterm Infants

Frontiers in Genetics, 2021
Idiopathic infantile arterial calcification (IIAC), also known as generalized arterial calcification of infancy (GACI), is a heritable ectopic mineralization disorder that results in diffuse arterial calcifications and or stenosis, which are attributed ...
Liu Yunfeng, Han Tongyan, Wang Jing, Tong Xiaomei   +3 more
doaj   +1 more source

Numerical study of TRIP transformation in 35NCD16 steel-effects of plate orientation and some criteria

Fracture and Structural Integrity, 2022
This study aims to analyze the effect of thermo mechanical coupling damage in the presence of a phase change (austenite/martensite) in 35NCD16 steel. The impact of increasing mechanical traction load, accompanied by a martensitic transformation on the ...
Mounir Gaci, Kamel Fedaoui, Lazhar Baroura, Amar Talhi   +3 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, Volume 16, Issue 3, Page 474-486, March 2026.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

A GPU‐Accelerated Generative Adversarial Model for Causal Inference

Concurrency and Computation: Practice and Experience, Volume 37, Issue 21-22, 25 September 2025.
ABSTRACT We develop a GPU‐accelerated machine learning generative adversarial model designed to facilitate causal inferences from observational data. Our model's theoretical framework is conceptualized in a manner that is amenable to being operable and scalable for high‐performance computing platforms. We leverage GPU acceleration to develop a parallel
Wendy K. Tam, Yan Y. Liu
wiley   +1 more source

Autologous bone grafting combined with spheroid‐based matrix‐induced autologous chondrocyte implantation for osteochondral defects of the knee: Good clinical outcomes alongside abnormal postoperative gait patterns

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 33, Issue 7, Page 2455-2469, July 2025.
Abstract Purpose This study aimed to evaluate the clinical and functional outcomes of autologous bone grafting with spheroid‐based matrix‐induced autologous chondrocyte implantation (MABCI) for osteochondral defects of the knee by analysing pre‐ and postoperative patient‐reported outcome measures (PROMs).
Stephan Oehme, Danko Dan Milinkovic, Azzurra Paolucci, Sophie Krafzick, Stephen Fahy, Philipp Damm, Tobias Winkler, Tobias Jung, Benjamin Bartek   +8 more
wiley   +1 more source

Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

MedComm, Volume 6, Issue 7, July 2025.
Phosphate serves as a building block for physiological mineralization, and as a signaling molecule that regulates the activity of mineralizing cells. The disturbance in these processes could induce a series of pathological mineralization, with abnormal mineralization of hard tissues and ectopic mineralization of soft tissues being the most ...
Wen Qin, San‐yang Yu, Jia‐lu Gao, Jian‐fei Yan, Qian‐qian Wan, Shuai‐lin Jia, Franklin Tay, Kai Jiao, Lina Niu   +8 more
wiley   +1 more source

DMPDS: A Fast Motion Estimation Algorithm Targeting High Resolution Videos and Its FPGA Implementation

International Journal of Reconfigurable Computing, 2012
This paper presents a new fast motion estimation (ME) algorithm targeting high resolution digital videos and its efficient hardware architecture design.
Gustavo Sanchez, Felipe Sampaio, Marcelo Porto, Sergio Bampi, Luciano Agostini   +4 more
doaj   +1 more source

Pharmacokinetics and Safety of Oral Pyrophosphate in Systemic Sclerosis Patients—A Pilot Study

ACR Open Rheumatology, Volume 7, Issue 4, April 2025.
Objective Calcinosis is a manifestation of systemic sclerosis with a severe negative impact on quality of life. Efforts to find a treatment for calcinosis have been hindered by our limited understanding of the underlying pathomechanism. We propose that extracellular pyrophosphate deficiency may have a causal role in the formation of these mineralized ...
Gergely Bodor, Márta Bocskai, Ágnes Dura, László Kovács, András Váradi, Eszter Kozák   +5 more
wiley   +1 more source