Investigation of HIV-1 Gag binding with RNAs and lipids using Atomic Force Microscopy. [PDF]
PLoS ONE, 2020 Atomic Force Microscopy was utilized to study the morphology of Gag, ΨRNA, and their binding complexes with lipids in a solution environment with 0.1Å vertical and 1nm lateral resolution. TARpolyA RNA was used as a RNA control. The lipid used was phospha-
Shaolong Chen +6 more
doaj +4 more sources
New Insights Into Retroviral Gag-Gag and Gag-Membrane Interactions [PDF]
Frontiers in Microbiology, 2014 A critical aspect of viral replication is the assembly of virus particles, which aresubsequently released as progeny virus. While a great deal of attention has beenfocused on better understanding this phase of the viral life cycle, many aspects of ...
Jose eMaldonado +4 more
doaj +4 more sources
Sequence Instability in the Proviral Long Terminal Repeat and gag Regions from Peripheral Blood and Tissue-Derived Leukocytes of FIV-Infected Cats during the Late Asymptomatic Phase [PDF]
Veterinary Sciences, 2016 Feline immunodeficiency virus (FIV) infection results in viral persistence, a prolonged asymptomatic phase, and progressive immunopathology. During the asymptomatic phase, a cohort of experimentally FIV-infected cats exhibits features of viral latency in
Christina D. Eckstrand +2 more
doaj +5 more sources
The tax-inducible actin-bundling protein fascin is crucial for release and cell-to-cell transmission of human T-cell leukemia virus type 1 (HTLV-1) [PDF]
, 2016 The delta-retrovirus Human T-cell leukemia virus type 1 (HTLV-1) preferentially infects CD4(+) T-cells via cell-to-cell transmission. Viruses are transmitted by polarized budding and by transfer of viral biofilms at the virological synapse (VS ...
Gettemans, Jan +6 more
core +18 more sources
Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice [PDF]
Viruses, 2021 Immature HIV virions harbor a lattice of Gag molecules with significant ordering in CA-NTD, CA-CTD and SP1 regions. This ordering plays a major role during HIV maturation. To test the condition in which the Gag lattice forms in vivo, we assembled virus like particles (VLPs) by expressing only HIV Gag in mammalian cells.
Ipsita Saha +8 more
openaire +4 more sources
Microbiology Spectrum, 2022 TRIM5α polymorphism in rhesus macaques (RM) limits the genetic pool of animals in which we can perform simian immunodeficiency virus (SIV) studies without first screening animals for permissive TRIM5α genotypes.
Cheri A. Lee, Vanessa M. Hirsch
doaj +1 more source
DISTINCTIVE SIRE1 RETROTRANSPOSON PATTERNS ON BARLEY CHROMOSOMES?
Trakya University Journal of Natural Sciences, 2021 SIRE1 is an active and relatively high copy-number retroelement belongs to the Tyl/Copia long terminal repeat (LTR) retrotransposon superfamily. Distinctive SIRE1 elements (ENV and GAG) distributions in barley genome were observed by using fluorescent in
Nermin Gozukirmizi, Elif Karlık
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Analysing the HERV-K env, np9, rec and gag expression in cervical tissues
New Microbes and New Infections, 2021 Cervical cancer is considered to be the fourth common cancer. It is assumed that numerous risk factors, especially infectious ones, can have a detrimental effect on cervical cancer.
S. Tavakolian +3 more
doaj +1 more source
Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
Viruses, 2021 Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl +6 more
doaj +1 more source
Glycosaminoglycan-Inspired Biomaterials for the Development of Bioactive Hydrogel Networks
Molecules, 2020 Glycosaminoglycans (GAG) are long, linear polysaccharides that display a wide range of relevant biological roles. Particularly, in the extracellular matrix (ECM) GAG specifically interact with other biological molecules, such as growth factors ...
Mariana I. Neves +4 more
doaj +1 more source