Results 151 to 160 of about 339,221 (330)

gag-Related polypeptides encoded by replication-defective avian oncoviruses [PDF]

open access: bronze, 1979
Carl W. Rettenmier   +3 more
openalex   +1 more source

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation

open access: yesAdvanced Science, EarlyView.
Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao   +18 more
wiley   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, EarlyView.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen   +9 more
wiley   +1 more source

Highly Efficient Air Sterilization via Low‐Temperature Interfacial Evaporation in Inductively Heated Superhydrophilic Ferromagnetic Filters

open access: yesAdvanced Science, EarlyView.
The first low‐temperature interfacial evaporation air sterilization technology is presented. It is based on a superhydrophilic ferromagnetic micro/nano‐structured stainless‐steel filter, showing ultra‐efficient inductive heating. This technology has demonstrated over 99.6% of SARS‐CoV‐2 and RSV elimination at temperatures in the 60–80 °C range.
Arnau Fons   +15 more
wiley   +1 more source

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