Results 101 to 110 of about 18,981 (340)

Galacto-Oligosaccharides : production, properties, applications, and significance as prebiotics [PDF]

, 2010
Galacto-oligosaccharides (GOS) have now been definitely established as prebiotic ingredients after in vitro and animal and human in vivo studies. Currently, GOS are produced by glycoside hydrolases (GH) using lactose as substrate.
[AOAC] Assn. of Official Analytical Chemists, [AOAC]Assn. of Official Analytical Chemists, Adam, Akiyama, Albayrak, Albayrak, Albayrak, Alles, Aronson, Aslan, Asp, Backhed, Bakker-Zierikzee, Ballio, Biggs, Bockmühl, Boehm, Boehm, Boon, Boon, Boon, Boon, Bouhnik, Bruins, Burr, Burvall, Cantarel, Cardelle-Cobas, Chen, Chen, Cheng, Cheng, Cheng, Cho, Chockchaisawasdee, Choi, Chonan, Coulier, Coutinho, Crittenden, Crout, Cruz, Cummings, Cummings, Czermak, Davies, De Roode, De Slegte, Del-Val, Del-Val, Depeint, DeVries, Drueckhammer, Dumortier, Ebrahimi, Ebrahimi, Engel, European Directive, European Regulation, Fanaro, Fanaro, Fanaro, Feng, Foda, Fox, Ganzle, Gaur, Gekas, Gibson, Gibson, Gibson, Gill, Gorin, Gorin, Goulas, Goulas, Goulas, Goulas, Greenberg, Grisdale-Helland, Hansson, Hansson, Harmsen, Hartemink, Henrissat, Henrissat, Hernandez, Houdijk, Houdijk, Hsu, Huber, Huh, Huh, Hung, Hung, Iqbal, Ishikawa, Ito, Ito, Iwasaki, Jeon, Ji, Jorgensen, Jung, Jung, Kim, Kim, Knol, Knol, Koshland, Krutmann, Kunz, Lairson, Leiva, Li, Li, Lifran, Lu, Lu, Lupp, Ly, Macfarlane, Macfarlane, Maischberger, Martinez-Villaluenga, Matella, Maugard, McCartney, Modesto, Moller, Monsan, Montanes, Moro, Mozaffar, Mozaffar, Mozaffar, Mwenya, Mwenya, Nakao, Nakayama, Nakkharat, Nakkharat, Neri, Neri, Newburg, Nguyen, Nobre, Ohtsuka, Ohtsuka, Onishi, Onishi, Onishi, Onishi, Onishi, Onishi, Paige, Panesar, Park, Paterson, Pazur, Pazur, Petzelbauer, Petzelbauer, Petzelbauer, Pivarnik, Placier, Playne, Prakash, Prakash, Prapulla, Prenosil, Rabiu, Rastall, Rehman, Richmond, Roberfroid, Roberfroid, Roberts, Roos, Ross, Rowland, Roy, Rustom, Sakai, Sako, Santoso, Sar, Schaafsma, Sekirov, Sheu, Shin, Shin, Silk, Sinclair, Sinnott, Splechtna, Splechtna, Splechtna, Stevenson, Tanaka, Toba, Toba, Toba, Tzortzis, Tzortzis, Tzortzis, Tzortzis, Van Loo, Vulevic, Wallenfels, Wallenfels, Widmer, Wikoff, Yanahira, Yang, Yang, Zechel, Zhou   +217 more
core   +1 more source

A Dual‐Targeting T6SS DNase Drives Bacterial Antagonism and Eukaryotic Apoptosis via the cGAS‐STING‐TNF Axis

Advanced Science, EarlyView.
The bacterial Type VI secretion system (T6SS) emerges as a sophisticated virulence mechanism, leveraging the dual‐function effector TkeA from Yersinia pseudotuberculosis. TkeA concurrently damages rival bacteria and host cell DNA, triggering the host's cGAS‐STING‐TNF pathway and inducing apoptosis.
Li Song, Lei Xu, Pengfei Zhang, Shuying Li, Yichen Qu, Yixin Zhao, Zhenkun Shi, Ruiqi Ma, Yongdong Li, Yi Chen, Yao Wang, Zhengfan Jiang, Gehong Wei, Xihui Shen   +13 more
wiley   +1 more source

Study of the transgalactosylation activity of ß-galactosidase from a new strain Kluyveromyces lactis 3 [PDF]

, 2012
Beta-galactosidase (EC.3.2.1.23) is an important enzyme industrially used for the hydrolysis of lactose from milk and milk whey for several applications.
ILIA ILIEV, TONKA VASILEVA
core  

Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria. [PDF]

, 2015
Breast milk enhances the predominance of Bifidobacterium species in the infant gut, probably due to its large concentration of human milk oligosaccharides (HMO). Here we screened infant-gut isolates of Bifidobacterium longum subsp.
Garrido, Daniel, German, J Bruce, Lemay, Danielle G, Mills, David A, Ruiz-Moyano, Santiago, Sela, David A   +5 more
core   +2 more sources

Tβ4‐Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing

Advanced Science, EarlyView.
A separable microneedle patch is designed for Tβ4–modified ADSC‐derived extracellular vesicles delivery. The overexpressed Tβ4 released from the microneedles can mitigate cellular senescence and promote wound healing via the PTEN/PI3K/AKT pathway, offering a promising approach for diabetic wound treatment. This bioengineered therapeutic system serve as
Youjun Ding, Jinglin Wang, Jiaye Li, Yi Cheng, Shuyin Zhou, Yepeng Zhang, Yuanjin Zhao, Min Zhou   +7 more
wiley   +1 more source

Intrinsic dynamic behavior of enzyme:substrate complexes govern the catalytic action of β-galactosidases across clan GH-A

Scientific Reports, 2019
The conformational itineraries taken by carbohydrate residues in the catalytic subsite of retaining glycoside hydrolases (GHs), harness the link between substrate conformation and reactivity.
Rajender Kumar, Bernard Henrissat, Pedro M. Coutinho   +2 more
doaj   +1 more source

EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer

Advanced Science, EarlyView.
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang, Xiaojun Zhang, Xupeng Yang, Xingshi Chen, Yuehong Wang, Jingying Hu, Rui Liu, Xiaoying Luo   +7 more
wiley   +1 more source

Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut [PDF]

, 2017
Bifidobacteria are common and frequently dominant members of the gut microbiota of many animals, including mammals and insects. Carbohydrates are considered key carbon sources for the gut microbiota, imposing strong selective pressure on the complex ...
Hevia, Arancha, Margolles Barros, Abelardo, Milani, Christian, Sánchez García, Borja, Ventura, Marco   +4 more
core   +1 more source

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

Advanced NanoBiomed Research, EarlyView.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang, Jingjing Wang, Long Ngo, Li Li, Yuling Wang   +4 more
wiley   +1 more source

Cheese and Yogurt By-Products as Valuable Ingredients for the Production of Prebiotic Oligosaccharides

Dairy
The growing global market of dairy products has led to the need for alternative approaches regarding whey valorization, which is the primary by-product of cheese and strained yogurt production.
Athanasios Limnaios, Maria Tsevdou, Eirini Zafeiri, Evangelos Topakas, Petros Taoukis   +4 more
doaj   +1 more source