Results 101 to 110 of about 14,424 (294)

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

open access: yesChemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida   +8 more
wiley   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

Genetics, cardiac phenotype and cardiovascular outcomes in Fabry disease patients in Finland

open access: yesESC Heart Failure, EarlyView.
Abstract Aims To investigate the genetics, cardiac phenotype and cardiovascular outcomes of Finnish Fabry patients. Methods and results Among the 109 patients with Fabry disease (FD) diagnosed in Finland by 2018, 97 (89%; 32 males and 65 females, mean ages 42 and 52 years) were followed for a mean of 12 years.
Kati Valtola   +5 more
wiley   +1 more source

Goat Milk‐Derived Extracellular Vesicles Attenuate Hydrogen Peroxide‐Treated Cell Damage in Human Skin Fibroblasts

open access: yesFood Frontiers, EarlyView.
2 types of goat milk extracellular vesicles (GMEVs‐1 and GMEVs‐2) were investigated for their migration and skin permeation abilities in vitro and in vivo. Using an H2O2‐induced model in human skin fibroblasts cells, we demonstrated their protective effects of against oxidative stress, highlighting their potential for skin health applications ...
Chunping Chen   +8 more
wiley   +1 more source

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