Results 201 to 210 of about 14,424 (294)

Tissue‐Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched‐Chain Amino Acids

Aging Cell, EarlyView.
Restriction of dietary BCAAs protects male mice from the metabolic consequences of both normal‐ and high‐protein diets. BCAA restriction also protects from hepatic cellular senescence in vivo and in vitro, especially in the context of mitochondrial stress. ABSTRACT Dietary protein is a key regulator of healthy aging in both mice and humans.
Mariah F. Calubag, Ismail Ademi, Isaac D. Grunow, Lucia E. Breuer, Reji Babygirija, Penelope Lialios, Sandra M. Le, Michelle M. Sonsalla, Julia A. Illiano, Bailey A. Knopf, Fan Xiao, Dennis Minton, Adam R. Konopka, David A. Harris, Dudley W. Lamming   +14 more
wiley   +1 more source

Survey of Some Actinomycetales for α-Galactosidase Activity1 [PDF]

, 1969
A. J. Lyons, T. G. Pridham, C. W. Hesseltine   +2 more
openalex   +1 more source

Mechanism-Based Allylic Carbasugar Chlorides That Form Covalent Intermediates with α- and β-Galactosidases. [PDF]

Molecules
Akintola O, Bhosale S, Bennet AJ.
europepmc   +1 more source

Properties and Regulation of the β- d -Galactosidase in Shigella dysenteriae and in Escherichia coli-Shigella dysenteriae Hybrids [PDF]

, 1966

openalex   +1 more source

Alternative Polyadenylation Contributes to Fibroblast Senescence in Pulmonary Fibrosis

Aging Cell, EarlyView.
In aging or fibrotic fibroblasts, NUDT21 is downregulated, leading to alternative polyadenylation/3′ UTR shortening of STAT3 pathway genes, enhancing their protein expression and promoting STAT3 phosphorylation. Activated STAT3 signaling subsequently drives the expression and release of senescence‐associated secretory phenotype (SASP) factors, thereby ...
Jingjing Huang, Maria Jose Gacha‐Garay, Yu Wang, Scott D. Collum, Rene A. Girard, Hydia Puente, Seung‐Hee Yoo, Rahat Hussain, Jayeshkumar Patel, Manish Patel, Eric J. Wagner, Hari KrishnaYalamanchili, Harry Karmouty‐Quintana, Zheng Chen, Tingting Mills   +14 more
wiley   +1 more source

Aspergillus foetidus as a potent producer for β-galactosidase utilizing lemon peels and coffee waste powder: production optimization, purification, kinetic and thermodynamic characterization. [PDF]

Microb Cell Fact
Wahab WAA, Saleh SAA, Elzairy NH, Ahmed SA, Zaki ER, Salama WH, Mostafa FA.   +6 more
europepmc   +1 more source

Distribution and Activity of Single β-d-Galactosidase Centers among Ribosomes of Escherichia coli

, 1964
Seymour Lederberg, Boris Rotman, Victoria Lederberg   +2 more
openalex   +1 more source

Single‐Cell Sequencing Reveals That CD4+ T Cells Eliminate Senescent Prostate Epithelium to Delay Progression of Benign Prostatic Hyperplasia

Aging Cell, EarlyView.
Senescent BPH epithelial cells secrete CXCL13 to recruit CD4+ T cells via CXCR5. Cytotoxic CD4+ T cells eliminate senescent cells through MHC‐II–dependent recognition. Tregs suppress, while B cells show minimal effect. This immune axis modulates senescent cell clearance and may influence BPH progression.
Zheng Li, Xiaofei Wang, Zhifu Liu, Senmao Li, Zhenan Zhang, Chenchen Huang, Yixiao Liu, Xingxing Tang, Jiaen Zhang, Peimin Zhou, Ying Gan, Yu Fan, Yisen Meng, Kaiwei Yang, Shuai Hu, Qian Zhang, Wei Yu   +16 more
wiley   +1 more source

cTAGE5/MEA6 Regulates LBR Localization to Maintain Nuclear Envelope Integrity and Safeguard Against Aging

Aging Cell, EarlyView.
cTAGE5 regulates LBR trafficking between the ER and the nucleus membrane to maintain the integrity of both the ER and the nuclear envelope. cTAGE5 KO results in LBR retention in the ER, reduced stability, and subsequent disruption of nuclear envelope integrity. ABSTRACT cTAGE5/MEA6 plays a pivotal role in COPII complex assembly, ER‐to‐Golgi trafficking,
Yaqing Wang, Pengyu Sun, Fuqiang Yang, Tiantian Ma, Junwan Fan, Lei Shi, Nan Li, Fei Gao, Kangmin He, Zhiheng Xu   +9 more
wiley   +1 more source

Biocatalytic Conversion of Carrageenans for the Production of 3,6-Anhydro-D-galactose. [PDF]

J Agric Food Chem
Fuchs A, Romeis D, Hupfeld E, Sieber V.
europepmc   +1 more source