Results 31 to 40 of about 10,260 (172)
Sex differences in gene expression with galactosylceramide treatment in Cln3Δex7/8 mice
PLoS ONE, 2020 Background CLN3 disease is caused by mutations in the CLN3 gene. The purpose of this study is to discern global expression patterns reflecting therapeutic targets in CLN3 disease.
Joelle Makoukji +6 more
doaj +2 more sources
Relationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulations. [PDF]
PLoS Computational Biology, 2014 A number of potentially bioactive molecules can be found in nature. In particular, marine organisms are a valuable source of bioactive compounds. The activity of an α-galactosylceramide was first discovered in 1993 via screening of a Japanese marine ...
Xavier Laurent +4 more
doaj +1 more source
Clinical & Translational Immunology, 2022 Objectives Metastasis is the principal cause of breast cancer mortality. Vaccines targeting breast cancer antigens have yet to demonstrate clinical efficacy, and there remains an unmet need for safe and effective treatment to reduce the risk of ...
Olivia K Burn +15 more
doaj +1 more source
Social disruption stress exacerbates alpha-galactosylceramide-induced hepatitis in mice [PDF]
, 2005 Objective: Psychosocial stress has been suggested as a possible aggravating factor in liver diseases, however, the underlying mechanism has yet to be clarified.
Chida, Y, Kubo, C, Sonoda, J, Sudo, N
core
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang +7 more
wiley +2 more sources
Polarity of neutral glycolipids, gangliosides, and sulfated lipids in MDCK epithelial cells.
Journal of Lipid Research, 1988 Confluent monolayers of MDCK (Madin-Darby canine kidney) cells provide a widely used model system for studying epithelial cell polarity. We determined the polarity of epithelial cell plasma membrane glycolipids and sulfated lipids by analyzing the lipids
G E Nichols, T Shiraishi, W W Young, Jr
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Fatty acid hydroxylase‐associated neurodegeneration (FAHN) is an ultra‐rare neurological disorder caused by a mutation in the FA2H gene. Defective production of this gene leads to abnormal myelin formation, which subsequently causes neurodegeneration and brain iron accumulation.
Araj Naveed Siddiqui +4 more
wiley +1 more source
Interactions between glucosylceramide and galactosylceramide I3 sulfate and microstructures formed [PDF]
, 2003 The monohexoside glycosphingolipids (GSLs), galactosylceramide (GalC), glucosylceramide (GluC), and their sulfated forms are abundant in cell membranes from a number of tissues.
Heng, Yew M, Boggs, Joan M, Dicko, Awa
core +1 more source
MedComm, Volume 7, Issue 10, October 2026.Peripheral nerve injury triggers axonal degeneration, myelin breakdown, and Schwann cell reprogramming. Remyelination requires reactivation of the SOX10–OCT6–KROX20/EGR2 transcriptional hierarchy, axonal NRG1–ErbB2/3 signaling, metabolic support, and coordinated immune regulation.
Li‐Xin Huang +13 more
wiley +1 more source
, 1996 Antibodies against the myelin glycolipid galactosylceramide are widely used to study the distribution and function of this molecule. However, anti-galactosylceramide antibodies are not monospecific and have been shown to recognize epitopes carried not ...
DE GASPERI, R. +11 more
core +1 more source