Results 71 to 80 of about 8,273 (177)

Developing an On‐Resin Synthesis of α‐Galactosylceramide‐Peptide Conjugate Vaccines

ChemistryEurope
The covalent attachment of peptide antigens to the NKT cell agonist, α‐galactosylceramide (αGalCer), generates self‐adjuvanting vaccines that prevent and/or eliminate disease in animal models of cancer and infectious disease.
Dr. Michael A. Meijlink, Dr. Susanna T. S. Chan, Kathryn J. Farrand, Sarah L. Draper, Dr. Oliva K. Burn, Jasmine M. Seifert‐Simpson, Ngarangi C. Mason, Dr. Lisa M. Connor, Prof. Ian F. Hermans, Prof. Gavin F. Painter, Dr. Benjamin J. Compton   +10 more
doaj   +1 more source

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

Scientific Reports, 2018
Lupus nephritis is a crucial complication of systemic lupus erythematosus. In this study, we investigated the roles of mouse natural killer T (NKT) cells in lupus nephritis.
Takahiro Uchida, Hiroyuki Nakashima, Akira Yamagata, Seigo Ito, Takuya Ishikiriyama, Masahiro Nakashima, Shuhji Seki, Hiroo Kumagai, Naoki Oshima   +8 more
doaj   +1 more source

Sulphated galactosylceramide [PDF]

Diabetologia, 2010
openaire   +2 more sources

Modulation of NKT cells and Th1/Th2 imbalance after α-GalCer treatment in progressive load-trained rats

International Journal of Biological Sciences, 2009
Purpose: The purpose of this study was to determine whether α-galactosylceramide (α-GalCer), a synthetic glycolipid agonist of natural killer T (NKT) cells, can ameliorate exercise-induced immune imbalance.
Wang Ru, Chen Peijie
doaj  

Alpha Galactosylceramide [PDF]

, 2020
openaire   +1 more source

<i>In vivo</i> stimulation of natural killer T cells and downstream regulatory T cells to reduce acute graft-versus-host disease. [PDF]

Ann Transl Med
Sluyter R, McErlean G.
europepmc   +1 more source

GAL3ST1-Mediated Histone Tyrosine Sulfation Induced by Cancer-Associated Fibroblasts Promotes Gastric Cancer Metastasis. [PDF]

Cancer Res
Lu Y, Wu X, Li B, Yao L, Hou J, Yu B, Li J, Li C, Yan M, Yang Z, Yan C, Zhu Z, Liu B, Tang K, Pan T, Yu Z, Jin Z, Su L.   +17 more
europepmc   +1 more source

Preclinical efficacy of combination therapy with allogeneic induced pluripotent stem cell-derived invariant natural killer T and α-galactosylceramide-pulsed antigen-presenting cells. [PDF]

Stem Cell Res Ther
Aoki T, Kobayashi M, Okoshi M, Yamaguchi M, Okura H, Sasaki S, Sasako Y, Kira S, Chang YH, Yakushiji-Kaminatsui N, Sharif J, Matsuda M, Kiuchi M, Hirahara K, Kimura MY, Motohashi S, Koseki H.   +16 more
europepmc   +1 more source

Brain lipid profiles and oligodendrocyte gene expression show discordant responses to high-fat diet in Alzheimer's disease mice. [PDF]

Sci Rep
Kawade N, Komine O, Sobue A, Kakimi C, Tanaka M, Suganami T, Shimada M, Ogi T, Ikeda K, Horiuchi M, Watanabe S, Saito T, Yamanaka K.   +12 more
europepmc   +1 more source

α-Galactosylceramide-expanded virtual memory CD8⁺ T cells confer protection against a broad range of pathogens. [PDF]

Front Immunol
Xie JX, Li DL, Lai MC, Su YL, Tai C, Wang CC, Lin JS.   +6 more
europepmc   +1 more source