Results 91 to 100 of about 21,078 (260)

Efficient synthesis of galanthamine

, 2013
The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof.
Philip D. Magnus, Neeraj Sane, Ben Fauber   +2 more
openaire   +2 more sources

Cytotoxicity Studies of Lycorine Alkaloids of the Amaryllidaceae

Natural Product Communications, 2014
The plant family Amaryllidaceae is renowned for its unique alkaloid constituents which possess a significant array of structural diversity. Several of these alkaloids are known for their interesting biological properties, of which galanthamine and ...
Jerald J. Nair, Johannes van Staden
doaj   +1 more source

Dissecting specialized metabolism in space: A MALDI-MSI atlas of Amaryllidaceae alkaloids in Hippeastrum papilio (Ravenna) Van Scheepen

Current Plant Biology
Amaryllidoideae produce specific specialized metabolites called Amaryllidaceae alkaloids (AAs), known for their pharmacological potential. The spatial distribution and biosynthesis within plant tissues, however, remain poorly understood.
Nuwan Sameera Liyanage, Natacha Mérindol, Sajjad Sobhanverdi, Kenneth Munk Pedersen, Christian Janfelt, Isabel Desgagné-Penix   +5 more
doaj   +1 more source

Representation and Treatment of Haemofilia in the general populaton in Macedonia [PDF]

, 2012
Introduction: Defects in blood coagulation can be congenital or acquired. Haemophilia belongs to the congenital (hereditary) coagulopathies.It is inherited recessively by a mutant gene located on the X-chromosome, therefore it affects only men. Women are
Velickova, Nevenka
core  

Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases [PDF]

, 2015
Age-associated neurodegenerative disorders such as Alzheimer’s disease are a major public health challenge, due to the demographic increase in the proportion of older individuals in society.
A Gutierrez-Zepeda, A Hornsten, A Lublin, A Murakami, A Tauffenberger, A Teixeira-Castro, A Teixeira-Castro, A Vaccaro, Alan Morgan, AR Burns, AV McCormick, B Lakowski, B Wolozin, BA Benitez, BB Kautu, BC Kraemer, BH Shin, BP Hubbard, C Fatouros, C Frokjaer-Jensen, C Soto, C Voisine, C Yao, CD Link, CD Link, CD Link, CD Link, CI Nussbaum-Krammer, CJ Locke, CY Ewald, D Levitan, DC Swinney, DC Swinney, DE Ehrnhoefer, DF Silva, DF Tardiff, DP Karpinar, DS Fay, E Braungart, EM Mandelkow, F Aparecida Paiva, F Cabreiro, F-X Lejeune, G McColl, G Pani, H Varma, H Wang, H Witan, HR Brignull, HV McCue, J Drake, J Li, J Liu, J Parker, J Parker, J Sämann, J Wang, JA Baur, JA Hardaway, Jeff W. Barclay, JF Morley, JN Sleigh, JP Taylor, JS Sangha, JV Smith, JW Barclay, K Evason, K Yamanaka, K-W Park, KA Caldwell, KE Matlack, L Diomede, L Diomede, L Noskova, L Xiao, LE Dosanjh, LS Schneider, M Briese, M Cadieux-Dion, M Haltia, M Haltia, M Lakso, M Marvanova, M Velinov, ML Florez-McClure, N Bizat, N Bizat, N Wittenburg, NF Liachko, NF Liachko, NT Christie, P Haldimann, PE Ash, PJ Muchowski, PW Faber, Q Ruan, R Brandt, R Keowkase, R Nass, R Nass, R Ved, R-H Fu, R-H Fu, RA Weiss, RD Burgoyne, Robert D. Burgoyne, S Abbas, S Abbas, S Alavez, S Amor, S Ayyadevara, S Buttner, S Cao, S Hamamichi, S Jagota, S Saha, S Treusch, SH Satyal, SJ Park, SM Yatin, SS Karuppagounder, SS Kashyap, T Gidalevitz, T Ham van, T Kuwahara, T Kuwahara, T Kuwahara, T Miyasaka, T Oeda, T Zhang, TJ Ham van, TT Ching, U Arya, V Crunelli, V Dostal, W Springer, X Chen, X Chen, X Yang, Xi Chen, Y Wu, Z Liu   +141 more
core   +1 more source

Enhancement of alkaloid content (galanthamine and lycorine) and antioxidant activities (enzymatic and non-enzymatic) unders salt stress in summer snowflake (Leucojum aestivum L.)

, 2021
Muhammed Tural Ates, Arzu Birinci Yıldırım, Arzu Uçar Türker   +2 more
openalex   +1 more source

The cyanobacterial alkaloid nostocarboline: an inhibitor of acetylcholinesterase and trypsin [PDF]

, 2018
Preselected cyanobacterial strains (available from culture collections and our own isolates), belonging primarily to the heterocystous cluster, were screened for inhibitors against butyrylcholinesterase.
Baumann, Heike, Becher, Paul, Gademann, Karl, Jüttner, Friedrich   +3 more
core  

Rising CO2, Climate Change, and Public Health: Exploring the Links to Plant Biology [PDF]

, 2011
Background: Although the issue of anthropogenic climate forcing and public health is widely recognized, one fundamental aspect has remained underappreciated: the impact of climatic change on plant biology and the well-being of human systems.
Epstein, Paul Robert, Schlesinger, William H., Ziska, Lewis H.   +2 more
core   +1 more source

Acetylcholinesterase inhibition by somes promising Brazilian medicinal plants

Brazilian Journal of Biology
A microplate assay and a thin-layer chromatography (TLC) "in situ" assay based on the Ellman assay was used to screen for acetylcholinesterase inhibitors from ethyl acetate and methanol extracts of Brazilian medicinal plants of families that, according ...
CM. Feitosa, RM. Freitas, NNN. Luz, MZB. Bezerra, MTS. Trevisan   +4 more
doaj   +1 more source

Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]

, 2018
Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
core   +1 more source