Galanthamine production by
Vasil Georgiev +6 more
openalex +1 more source
Esenbeckia leiocarpa Engl. (Rutaceae), popularly known as guarantã, goiabeira, is a native tree from Brazil. Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, leptomerine, kokusaginine ...
Elaine Monteiro Cardoso-Lopes +8 more
doaj +1 more source
Characterization of hepatic enzyme activity in older adults with dementia: potential impact on personalizing pharmacotherapy [PDF]
OBJECTIVE: To determine the frequency of pharmacogenomic variants and concurrent medications that may alter the efficacy and tolerability of acetylcholinesterase inhibitors (AChEIs).
Boustani, Malaz A. +6 more
core +2 more sources
The evaluation of cognitive function in the dementias: methodological and regulatory considerations [PDF]
This is the final version of the article. Available from the publisher via the NCBI link in this record.Impairment of cognitive function is the central feature of dementia. Although, clinically, the cognitive deficit most often manifests itself as memory
Harrison, JE, Wesnes, KA
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The generalist inside the specialist: gut bacterial communities of two insect species feeding on toxic plants are dominated by enterococcus sp. [PDF]
Some specialist insects feed on plants rich in secondary compounds, which pose a major selective pressure on both the phytophagous and the gut microbiota. However, microbial communities of toxic plant feeders are still poorly characterized. Here, we show
Baixeras, Joaquín +3 more
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(E)-2-(benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles are described as a new class of selective inhibitors of acetylcholinesterase (AChE). The most potent compound in the series exhibited good AChE inhibitory activity (IC50 = 64 µM). Compound
Jorge Trilleras +6 more
doaj +1 more source
Analysis of Amaryllidaceae Alkaloids from by GC-MS and their Cholinesterase Activity
The underivatized alkaloid mixture extracted from the bulbs of Chlidanthus fragrans Herb. was investigated by capillary GC/MS for the first time. Fifteen known Amaryllidaceae alkaloids of five structure types were identified.
Lucie Cahlíková +6 more
doaj +1 more source
Antioxidant, Anti-5-lipoxygenase and Antiacetylcholinesterase Activities of Essential Oils and Decoction Waters of Some Aromatic Plants [PDF]
The scavenging of free radicals and superoxide anion, the inhibition of 5-lipoxygenase and the antiacetylcholinesterase activities of essential oils and decoction waters of eight aromatic plants (Dittrichia viscosa, Foeniculum vulgare, Origanum vulgare ...
Albano, Sílvia +5 more
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Chemical Composition and Enzyme Inhibitory Activities of Turkish Bulbs
The chemical composition of the bulbs of Pancratium maritimum L. (Amaryllidaceae) from Turkey (Pamucak, Aydın) has been determined by gas chromatography-mass spectrometry.
Buket Bozkurt +2 more
doaj +1 more source
Cannabinoid CB1 receptor binding and acetylcholinesterase inhibitory activity of Sceletium tortuosum L. [PDF]
The whole plant extract of plant Sceletium tortuosum, plant native to South Africa, has been known traditionally to have mood enhancing and stimulant properties. These properties have been confirmed before by proving serotonin-uptake inhibition activity.
Khatib, Alfi +4 more
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