Results 101 to 110 of about 21,078 (260)

Galanthamine production by Leucojum aestivumL. shoot culture in a modified bubble column bioreactor with internal sections [PDF]

open access: bronze, 2012
Vasil Georgiev   +6 more
openalex   +1 more source

Alkaloids from Stems of Esenbeckia leiocarpa Engl. (Rutaceae) as Potential Treatment for Alzheimer Disease

open access: yesMolecules, 2010
Esenbeckia leiocarpa Engl. (Rutaceae), popularly known as guarantã, goiabeira, is a native tree from Brazil. Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, leptomerine, kokusaginine ...
Elaine Monteiro Cardoso-Lopes   +8 more
doaj   +1 more source

Characterization of hepatic enzyme activity in older adults with dementia: potential impact on personalizing pharmacotherapy [PDF]

open access: yes, 2015
OBJECTIVE: To determine the frequency of pharmacogenomic variants and concurrent medications that may alter the efficacy and tolerability of acetylcholinesterase inhibitors (AChEIs).
Boustani, Malaz A.   +6 more
core   +2 more sources

The evaluation of cognitive function in the dementias: methodological and regulatory considerations [PDF]

open access: yes, 2018
This is the final version of the article. Available from the publisher via the NCBI link in this record.Impairment of cognitive function is the central feature of dementia. Although, clinically, the cognitive deficit most often manifests itself as memory
Harrison, JE, Wesnes, KA
core  

The generalist inside the specialist: gut bacterial communities of two insect species feeding on toxic plants are dominated by enterococcus sp. [PDF]

open access: yes, 2016
Some specialist insects feed on plants rich in secondary compounds, which pose a major selective pressure on both the phytophagous and the gut microbiota. However, microbial communities of toxic plant feeders are still poorly characterized. Here, we show
Baixeras, Joaquín   +3 more
core   +1 more source

A Novel Class of Selective Acetylcholinesterase Inhibitors: Synthesis and Evaluation of (E)-2-(Benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles

open access: yesMolecules, 2012
(E)-2-(benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles are described as a new class of selective inhibitors of acetylcholinesterase (AChE). The most potent compound in the series exhibited good AChE inhibitory activity (IC50 = 64 µM). Compound
Jorge Trilleras   +6 more
doaj   +1 more source

Analysis of Amaryllidaceae Alkaloids from by GC-MS and their Cholinesterase Activity

open access: yesNatural Product Communications, 2011
The underivatized alkaloid mixture extracted from the bulbs of Chlidanthus fragrans Herb. was investigated by capillary GC/MS for the first time. Fifteen known Amaryllidaceae alkaloids of five structure types were identified.
Lucie Cahlíková   +6 more
doaj   +1 more source

Antioxidant, Anti-5-lipoxygenase and Antiacetylcholinesterase Activities of Essential Oils and Decoction Waters of Some Aromatic Plants [PDF]

open access: yes, 2012
The scavenging of free radicals and superoxide anion, the inhibition of 5-lipoxygenase and the antiacetylcholinesterase activities of essential oils and decoction waters of eight aromatic plants (Dittrichia viscosa, Foeniculum vulgare, Origanum vulgare ...
Albano, Sílvia   +5 more
core  

Chemical Composition and Enzyme Inhibitory Activities of Turkish Bulbs

open access: yesNatural Product Communications, 2019
The chemical composition of the bulbs of Pancratium maritimum L. (Amaryllidaceae) from Turkey (Pamucak, Aydın) has been determined by gas chromatography-mass spectrometry.
Buket Bozkurt   +2 more
doaj   +1 more source

Cannabinoid CB1 receptor binding and acetylcholinesterase inhibitory activity of Sceletium tortuosum L. [PDF]

open access: yes, 2010
The whole plant extract of plant Sceletium tortuosum, plant native to South Africa, has been known traditionally to have mood enhancing and stimulant properties. These properties have been confirmed before by proving serotonin-uptake inhibition activity.
Khatib, Alfi   +4 more
core  

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