Results 41 to 50 of about 3,073 (217)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

Causal Discovery in Astrophysics: Unraveling Supermassive Black Hole and Galaxy Coevolution

The Astrophysical Journal
Correlation does not imply causation, but patterns of statistical association between variables can be exploited to infer a causal structure (even with purely observational data) with the burgeoning field of causal discovery.
Zehao Jin, Mario Pasquato, Benjamin L. Davis, Tristan Deleu, Yu Luo, Changhyun Cho, Pablo Lemos, Laurence Perreault-Levasseur, Yoshua Bengio, Xi Kang, Andrea Valerio Macciò, Yashar Hezaveh   +11 more
doaj   +1 more source

Gas Accretion Can Drive Turbulence in Galaxies

The Astrophysical Journal, 2023
The driving of turbulence in galaxies is deeply connected with the physics of feedback, star formation, outflows, accretion, and radial transport in disks.
John C. Forbes, Razieh Emami, Rachel S. Somerville, Shy Genel, Dylan Nelson, Annalisa Pillepich, Blakesley Burkhart, Greg L. Bryan, Mark R. Krumholz, Lars Hernquist, Stephanie Tonnesen, Paul Torrey, Viraj Pandya, Christopher C. Hayward   +13 more
doaj   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Seedless One‐Pot Synthesis of Colloidal InAs Quantum Dots Enabling a High‐Accuracy Photoplethysmography Oximeter

Advanced Science, EarlyView.
A real‐time, non‐contact photoplethysmography (PPG) system based on InAs colloidal quantum dots (CQDs) synthesized via a seedless injection synthesis is demonstrated. The measured oxygen saturation shows considerable agreement with commercial PPG devices.
Beom Kwan Kim, Seungin Jee, Yongnam Ahn, In‐Suh Lee, Dongeon Kim, Seongchong Park, Yujin Jung, In‐Ho Bae, Se‐Woong Baek   +8 more
wiley   +1 more source

How Do Uncertainties in Galaxy Formation Physics Impact Field-level Galaxy Bias?

The Astrophysical Journal
Our ability to extract cosmological information from galaxy surveys is limited by uncertainties in the galaxy–dark matter halo relationship for a given galaxy population, which are governed by the intricacies of galaxy formation.
Mahlet Shiferaw, Nickolas Kokron, Risa H. Wechsler   +2 more
doaj   +1 more source

Silicon‐Embedded Multifunctional Heterogeneous Integration for Miniaturized Photoplethysmography Detection Devices

Advanced Science, EarlyView.
ABSTRACT The multifunctional integration of chips with high flexibility and scalable manufacturing is crucial for enhancing chip performance, reducing chip size, and simplifying chip design. However, balancing volume, cost, flexibility, and functionality using traditional heterogeneous integration methods is challenging.
Lang Chen, Shizun Hu, Zhou Yang, Shitao Shen, Pan Zhang, Han Xu, Chi Zhang, Wei Wang   +7 more
wiley   +1 more source

A MaNGA about the Legacy. I. Connecting the Assembly of Stellar Halo with the Average Star Formation History in Low-redshift Massive Galaxies

The Astronomical Journal
We investigate the connection between stellar mass distribution, assembly history, and star formation timescales in low-redshift massive early-type galaxies (ETGs) by combining deep LegacySurvey imaging with MaNGA’s spatially resolved spectroscopy ...
Xiaoya Zhang, Song Huang, Meng Gu
doaj   +1 more source

A Review of Failure Modes and Safety Strategies of Lithium‐Ion Batteries from Materials to Systems

Advanced Science, EarlyView.
A cascade‐aware framework is presented for lithium‐ion battery safety, linking thermal runaway initiation, acceleration, runaway reaction, and propagation with material‐, cell/pack‐, and system‐level interventions. By integrating failure mechanisms, quantitative safety indicators, and staged interception strategies, this review highlights how safer ...
Jin Hyeok Yang, Jae Yoon Sung, Hyunji Kweon, Seohyun Kim, Byunghoon Kim, Jongsoon Kim, Junyoung Mun, Jung Ho Kim, Ki Jae Kim   +8 more
wiley   +1 more source