Results 31 to 40 of about 4,258,326 (225)

Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]

, 2002
The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Holíkova, Zuzana, Kaltner, Herbert, Motlik, Jan, Gabius, Hans-Joachim, Plzák, Jan, Smetana, Karel, Hercogová, Jana, Dvorankova, Barbora   +7 more
core   +1 more source

Prognostic significance of endogenous adhesion/growth-regulatory lectins in lung cancer [PDF]

, 2005
Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins and their binding sites using labeled tissue lectins as well as the binding profile of hyaluronic acid as an approach to define new prognostic markers.
Szöke, Tamas, Furak, Jozsef, André, Sabine, Kayser, Klaus, Horvath, Akos, Baumhäkel, Jan-Dirk, Gabius, Hans-Joachim, Trojan, Imre, Szluha, Kornelia, Tiszlavicz, Laszlo   +9 more
core   +1 more source

Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis [PDF]

, 2021
Galectin-9 is a member of the galectin family of proteins, which were first identified to specifically bind to carbohydrates containing β-galactosides. Galectin-9 is conserved through evolution and recent evidence demonstrated its involvement in innate ...
Sumbayev, Vadim V., Schlichtner, Stephanie, Gibbs, Bernhard F, Yasinska, Inna M., Fasler-Kan, Elizaveta, Gibbs, Bernhard F., Aliu, Nijas, Berger, Steffen M., Meyer, N. Helge, Helge Meyer, N.   +9 more
core   +1 more source

Galectin-9 inhibits cell proliferation and induces apoptosis in Jurkat and KE-37 acute lymphoblastic leukemia cell lines via caspase-3 activation

Research in Pharmaceutical Sciences, 2021
Background and purpose: Acute lymphoblastic leukemia (ALL) is a type of cancer of blood and bone marrow characterized by abnormal proliferation of lymphoid progenitor cells. Galectin-9 is a tandem-repeat type galectin expressed in various tumor cells. It
Narges Zargar Balajam, Mahdi Shabani, Mahmoud Aghaei   +2 more
doaj   +1 more source

Influence of Galectin-9 Treatment on the Phenotype and Function of NK-92MI Cells in the Presence of Different Serum Supplements

Biomolecules, 2021
Galectins are one of the critical players in the tumor microenvironment–tumor crosstalk and the regulation of local immunity. Galectin-9 has been in the limelight in tumor immunology.
Matyas Meggyes, David U Nagy, Timea Balassa, Krisztina Godony, Agnes Peterfalvi, Laszlo Szereday, Beata Polgar   +6 more
doaj   +1 more source

Human Galectins Induce Conversion of Dermal Fibroblasts into Myofibroblasts and Production of Extracellular Matrix: Potential Application in Tissue Engineering and Wound Repair [PDF]

, 2011
Members of the galectin family of endogenous lectins are potent adhesion/growth-regulatory effectors. Their multi-functionality opens possibilities for their use in bioapplications. We studied whether human galectins induce the conversion of human dermal
Lacina, Lukas, André, Sabine, Kaltner, Herbert, Karel Smetana, Jr., Gabius, Hans-Joachim, Peter Gal, Szabo, Pavol, Eva Sykova, Gal, Peter, Zima, Tomas, Sabine André, Tomas Zima, Smetana, Karel, Pavol Szabo, Barbora Dvořánková, Dvorankova, Barbora, Hans-Joachim Gabius, Jana Uhrova, Sykova, Eva, Lukas Lacina, Uhrova, Jana, Herbert Kaltner   +21 more
core   +1 more source

A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses

Infectious Agents and Cancer, 2012
Background Galectin-9 is a mammalian lectin which possesses immunosuppressive properties. Excessive production of galectin-9 has been reported in two types of human virus-associated diseases chronic hepatitis C and nasopharyngeal carcinoma associated to ...
Barjon Clément, Niki Toshiro, Vérillaud Benjamin, Opolon Paule, Bedossa Pierre, Hirashima Mitsuomi, Blanchin Stéphanie, Wassef Michel, Rosen Hugo R, Jimenez Anne-Sophie, Wei Ming, Busson Pierre   +11 more
doaj   +1 more source

Clinical Significance of Serum Galectin-9 and Soluble CD155 Levels in Patients with Systemic Sclerosis

Journal of Immunology Research, 2018
Signaling through coinhibitory receptors downregulates the immune response to prevent excessive immune activation and maintain optimal immunity and tolerance.
Mami Chihara, Miki Kurita, Yuki Yoshihara, Akihiko Asahina, Koichi Yanaba   +4 more
doaj   +1 more source

Galectin-1 immunofluorescent staining.

, 2023
Nuclei are labeled by Hoescht stain (blue, left panels). Gall bladder neuroendocrine neoplasm demonstrates positive galectin-1 (red, middle and right top panels) immunofluorescence compared to negative control (normal canine kidney).
Daniel Paulsen (5500241), Andrea N. Johnston (14504545), Bonnie Boudreaux (10895018), Emi Sasaki (11981004), Chin-Chi Liu (9210758), Joshua Sparago (14504539), Stephanie D. Byrum (3873991), Mayzie Miller (14504536), Tifini L. Batts (14504533), Rudy W. Bauer (14504542)   +9 more
core   +1 more source

Immunomodulator Galectin-9 is Increased in Blood and Skin of Patients with Bullous Pemphigoid

Acta Dermato-Venereologica, 2021
Massive recruitment of eosinophils into the dermis is a hallmark of bullous pemphigoid pathogenesis. Identifying the chemoattractant(s) guiding eosinophils into the skin in bullous pemphigoid is a prerequisite to thera­peutic targeting of eosinophil ...
Jasper Pruessmann, Wiebke Pruessmann, Maike M. Holtsche, Beke Linnemann, Christoph M. Hammers, Nina van Beek, Detlef Zillikens, Enno Schmidt, Christian D. Sadik   +8 more
doaj   +1 more source